Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 375.8 BDBM50317480

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50317480 ((S)-2-(2-((4-(4-chlorophenoxy)phenoxy)methyl)piper...) Show SMILES OC(=O)CN1CCCC[C@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C20H22ClNO4/c21-15-4-6-18(7-5-15)26-19-10-8-17(9-11-19)25-14-16-3-1-2-12-22(16)13-20(23)24/h4-11,16H,1-3,12-14H2,(H,23,24)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MS				Bioorg Med Chem Lett 20: 2851-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.047 BindingDB Entry DOI: 10.7270/Q2CC10VD
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