Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Delta-aminolevulinic acid dehydratase, chloroplastic
(Pisum sativum) | BDBM50017195
(CHEMBL2430557)Show SMILES OC(=O)c1c2CN(CCc2nc2ccccc12)C(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O3/c22-21(23,24)13-5-3-4-12(10-13)19(27)26-9-8-17-15(11-26)18(20(28)29)14-6-1-2-7-16(14)25-17/h1-7,10H,8-9,11H2,(H,28,29) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn
Curated by ChEMBL
| Assay Description Inhibition of Pisum sativum PBGS using 5-ALA as substrate |
J Med Chem 57: 2498-510 (2014)
Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 |
More data for this Ligand-Target Pair | |
Delta-aminolevulinic acid dehydratase
(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...) | BDBM50017195
(CHEMBL2430557)Show SMILES OC(=O)c1c2CN(CCc2nc2ccccc12)C(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O3/c22-21(23,24)13-5-3-4-12(10-13)19(27)26-9-8-17-15(11-26)18(20(28)29)14-6-1-2-7-16(14)25-17/h1-7,10H,8-9,11H2,(H,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.75E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn
Curated by ChEMBL
| Assay Description Inhibition of Pseudomonas aeruginosa PAO1 recombinant PBGS using 5-ALA as substrate |
J Med Chem 57: 2498-510 (2014)
Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 |
More data for this Ligand-Target Pair | |
Delta-aminolevulinic acid dehydratase
(Homo sapiens (Human)) | BDBM50017195
(CHEMBL2430557)Show SMILES OC(=O)c1c2CN(CCc2nc2ccccc12)C(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O3/c22-21(23,24)13-5-3-4-12(10-13)19(27)26-9-8-17-15(11-26)18(20(28)29)14-6-1-2-7-16(14)25-17/h1-7,10H,8-9,11H2,(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn
Curated by ChEMBL
| Assay Description Inhibition of human PBGS using 5-ALA as substrate |
J Med Chem 57: 2498-510 (2014)
Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 |
More data for this Ligand-Target Pair | |
Delta-aminolevulinic acid dehydratase
(Drosophila melanogaster) | BDBM50017195
(CHEMBL2430557)Show SMILES OC(=O)c1c2CN(CCc2nc2ccccc12)C(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O3/c22-21(23,24)13-5-3-4-12(10-13)19(27)26-9-8-17-15(11-26)18(20(28)29)14-6-1-2-7-16(14)25-17/h1-7,10H,8-9,11H2,(H,28,29) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of Bonn
Curated by ChEMBL
| Assay Description Inhibition of Drosophila melanogaster recombinant PBGS using 5-ALA as substrate |
J Med Chem 57: 2498-510 (2014)
Article DOI: 10.1021/jm401785n BindingDB Entry DOI: 10.7270/Q2QZ2CJ8 |
More data for this Ligand-Target Pair | |