Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 482.5 BDBM50084819

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50084819 (4-(2-{[7-(Quinolin-2-ylmethoxy)-chroman-2-carbonyl...) Show SMILES OC(=O)c1ccc(CCNC(=O)C2CCc3ccc(OCc4ccc5ccccc5n4)cc3O2)cc1 Show InChI InChI=1S/C29H26N2O5/c32-28(30-16-15-19-5-7-22(8-6-19)29(33)34)26-14-11-21-10-13-24(17-27(21)36-26)35-18-23-12-9-20-3-1-2-4-25(20)31-23/h1-10,12-13,17,26H,11,14-16,18H2,(H,30,32)(H,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	237	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorios Menarini Curated by ChEMBL					Assay Description In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes				J Med Chem 43: 392-400 (2000) BindingDB Entry DOI: 10.7270/Q2DJ5DVX
					More data for this Ligand-Target Pair