Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM345819
(US10202362, Compound T2.2)Show SMILES OC(=O)c1ccc(CN2CCCC(CNc3ccc(Oc4ccc(Cl)cc4)cc3)C2)cc1 Show InChI InChI=1S/C26H27ClN2O3/c27-22-7-11-24(12-8-22)32-25-13-9-23(10-14-25)28-16-20-2-1-15-29(18-20)17-19-3-5-21(6-4-19)26(30)31/h3-14,20,28H,1-2,15-18H2,(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Celtaxsys, Inc.
US Patent
| Assay Description
LTB4 formed was quantified with the HTRF assay in which free LTB4 competes with LTB4-XL665 conjugate (acceptor) for anti-LTB4 monoclonal antibody lab... |
US Patent US10202362 (2019)
BindingDB Entry DOI: 10.7270/Q2MC9241 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM345819
(US10202362, Compound T2.2)Show SMILES OC(=O)c1ccc(CN2CCCC(CNc3ccc(Oc4ccc(Cl)cc4)cc3)C2)cc1 Show InChI InChI=1S/C26H27ClN2O3/c27-22-7-11-24(12-8-22)32-25-13-9-23(10-14-25)28-16-20-2-1-15-29(18-20)17-19-3-5-21(6-4-19)26(30)31/h3-14,20,28H,1-2,15-18H2,(H,30,31) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Celtaxsys, Inc.
US Patent
| Assay Description
In brief, the enzyme (29 nM) was incubated with L-alanine-p-nitroanilide (1 mM) in 50 mM HEPES (pH 7.5), 100 mM KCL, 1% DMSO in the absence or presen... |
US Patent US10202362 (2019)
BindingDB Entry DOI: 10.7270/Q2MC9241 |
More data for this
Ligand-Target Pair | |