Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 384.5 BDBM50095684

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50095684 (2-Cyclopentyl-N-(1-cyclopentylmethyl-piperidin-4-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(CC2CCCC2)CC1)c1ccccc1 Show InChI InChI=1S/C24H36N2O2/c27-23(24(28,21-12-6-7-13-21)20-10-2-1-3-11-20)25-22-14-16-26(17-15-22)18-19-8-4-5-9-19/h1-3,10-11,19,21-22,28H,4-9,12-18H2,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M3 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50095684 (2-Cyclopentyl-N-(1-cyclopentylmethyl-piperidin-4-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(CC2CCCC2)CC1)c1ccccc1 Show InChI InChI=1S/C24H36N2O2/c27-23(24(28,21-12-6-7-13-21)20-10-2-1-3-11-20)25-22-14-16-26(17-15-22)18-19-8-4-5-9-19/h1-3,10-11,19,21-22,28H,4-9,12-18H2,(H,25,27)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M1 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50095684 (2-Cyclopentyl-N-(1-cyclopentylmethyl-piperidin-4-y...) Show SMILES OC(C1CCCC1)(C(=O)NC1CCN(CC2CCCC2)CC1)c1ccccc1 Show InChI InChI=1S/C24H36N2O2/c27-23(24(28,21-12-6-7-13-21)20-10-2-1-3-11-20)25-22-14-16-26(17-15-22)18-19-8-4-5-9-19/h1-3,10-11,19,21-22,28H,4-9,12-18H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-NMS binding to human muscarinic acetylcholine receptor M2 expressed in CHO cells				J Med Chem 43: 5017-29 (2001) BindingDB Entry DOI: 10.7270/Q2HM57P7
					More data for this Ligand-Target Pair