SMILES String Search

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 147.1
BDBM50240725

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 18 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen debranching enzyme (Oryctolagus cuniculus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rabbit muscle amylo-1,6-glucosidase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Mus musculus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...				ACS Med Chem Lett 2: 519-522 (2011) Article DOI: 10.1021/ml200050s BindingDB Entry DOI: 10.7270/Q28916V8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-galactosidase (Rattus norvegicus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Concentration that causes 50% inhibition of mammalian lactase beta-galactosidase was determined in rat intestine				J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometry				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal isomaltase assessed as production of p-nitrophenol at by spectrophotometry				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-galactosidase (Bos taurus (Bovine))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Concentration that causes 50% inhibition of mammalian cytosolic beta-galactosidase was determined in bovine liver				J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-galactosidase (Bos taurus (Bovine))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometry				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of Wistar rat intestinal isomaltase by glucose B-test				J Nat Prod 60: 312-4 (1997) Article DOI: 10.1021/np960646y BindingDB Entry DOI: 10.7270/Q2WQ03TX
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal brush border membrane sucrase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Homo sapiens (Human))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Concentration that causes 50% inhibition of mammalian alpha-L-fucosidase was determined in bovine epididymis				J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Bos taurus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...				Bioorg Med Chem 19: 3558-68 (2011) Article DOI: 10.1016/j.bmc.2011.04.011 BindingDB Entry DOI: 10.7270/Q2BC3ZWW
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral alpha-glucosidase C (Mus musculus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Concentration that causes 50% inhibition of mammalian alpha-glucosidase (isomaltase) was determined in rat intestine				J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal brush border membrane isomaltase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Bos taurus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of mammalian alpha-glucosidase (lysosomal) was determined in bovine liver				J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal brush border membrane maltase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Concentration that causes 50% inhibition of mammalian alpha-glucosidase (maltase) was determined in rat intestine				J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Neutral alpha-glucosidase AB (Homo sapiens (Human))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Concentration that causes 50% inhibition of mammalian alpha-mannosidase (golgi II) was determined in rat liver				J Med Chem 37: 3701-6 (1994) BindingDB Entry DOI: 10.7270/Q2ZC83H3
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Homo sapiens (Human))	BDBM50240725 ((2R,3R,4R)-2-Hydroxymethyl-piperidine-3,4-diol \| C...) Show SMILES OC[C@H]1NCC[C@@H](O)[C@@H]1O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysis				ACS Med Chem Lett 2: 519-522 (2011) Article DOI: 10.1021/ml200050s BindingDB Entry DOI: 10.7270/Q28916V8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair