Found 5 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007030
(CHEMBL3237548)Show SMILES OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1CC[C@@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5-,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM111585
(US8618075, 3a)Show SMILES OC[C@H]1OC([C@H](F)[C@@H]1O)N1CC[C@@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5-,6-,7-,8?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Eisai Inc.
US Patent
| Assay Description
The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19... |
US Patent US8618075 (2013)
BindingDB Entry DOI: 10.7270/Q20000RG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM111582
(US8618075, 3)Show SMILES OC[C@H]1OC([C@H](F)[C@@H]1O)N1CCC(O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5?,6-,7-,8?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Eisai Inc.
US Patent
| Assay Description
The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19... |
US Patent US8618075 (2013)
BindingDB Entry DOI: 10.7270/Q20000RG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM111580
(US8618075, 3b)Show SMILES OC[C@H]1OC([C@H](F)[C@@H]1O)N1CC[C@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5+,6-,7-,8?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Eisai Inc.
US Patent
| Assay Description
The procedure to determine CDA enzymatic activity is based on published methodologies (for example, Cacciamani, T. et al., Arch. Biochem. Biophys. 19... |
US Patent US8618075 (2013)
BindingDB Entry DOI: 10.7270/Q20000RG |
More data for this
Ligand-Target Pair | |
Cytidine deaminase
(Homo sapiens (Human)) | BDBM50007033
(CHEMBL3237551)Show SMILES OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1CC[C@H](O)NC1=O |r| Show InChI InChI=1S/C9H15FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h4-8,13-15H,1-3H2,(H,11,16)/t4-,5+,6-,7-,8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant cytidine deaminase assessed as cytidine to uridine formation |
J Med Chem 57: 2582-8 (2014)
Article DOI: 10.1021/jm401856k
BindingDB Entry DOI: 10.7270/Q2NK3GJG |
More data for this
Ligand-Target Pair | |