| Reaction Details |
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 | Report a problem with these data |
| Target | Cytidine deaminase |
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| Ligand | BDBM50007030 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1337494 (CHEMBL3241962) |
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| IC50 | 200±n/a nM |
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| Citation |  Ferraris, D; Duvall, B; Delahanty, G; Mistry, B; Alt, J; Rojas, C; Rowbottom, C; Sanders, K; Schuck, E; Huang, KC; Redkar, S; Slusher, BB; Tsukamoto, T Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem57:2582-8 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytidine deaminase |
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| Name: | Cytidine deaminase |
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| Synonyms: | CDA | CDD | CDD_HUMAN | Cytidine deaminase | Cytidine deaminase (CDA) |
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| Type: | Ezyme |
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| Mol. Mass.: | 16185.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32320 |
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| Residue: | 146 |
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| Sequence: | MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACY
PLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKP
DGTYIVMTVQELLPSSFGPEDLQKTQ
|
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| BDBM50007030 |
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| n/a |
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| Name | BDBM50007030 |
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| Synonyms: | CHEMBL3237548 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15FN2O5 |
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| Mol. Mass. | 250.2242 |
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| SMILES | OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1CC[C@@H](O)NC1=O |r| |
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| Structure | 
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