SMILES String Search

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 542.1
BDBM50312261

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis PtpA				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human HCPTPA				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human VHR				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase C (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human CD45				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human LAR				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human PTP1B				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human PtpB				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50312261 ((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human TCPTP				Bioorg Med Chem Lett 19: 6851-4 (2009) Article DOI: 10.1016/j.bmcl.2009.10.090 BindingDB Entry DOI: 10.7270/Q21G0MDK
University of California Curated by ChEMBL					More data for this Ligand-Target Pair