Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440924
(US10639284, Compound 3.093 | US11426364, Compound ...)Show SMILES Oc1ccc2CC[C@@H](Cc2c1)NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccccc2F)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C39H33ClFN3O3/c40-35-17-28(22-44-29-10-8-26-9-11-30(45)16-27(26)15-29)38(46-23-25-14-24(19-42)20-43-21-25)18-39(35)47-37-13-12-32-31(5-3-6-34(32)37)33-4-1-2-7-36(33)41/h1-7,9,11,14,16-18,20-21,29,37,44-45H,8,10,12-13,15,22-23H2/t29-,37-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2K93BSK |
More data for this
Ligand-Target Pair | |
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440924
(US10639284, Compound 3.093 | US11426364, Compound ...)Show SMILES Oc1ccc2CC[C@@H](Cc2c1)NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccccc2F)cc1OCc1cncc(c1)C#N |r| Show InChI InChI=1S/C39H33ClFN3O3/c40-35-17-28(22-44-29-10-8-26-9-11-30(45)16-27(26)15-29)38(46-23-25-14-24(19-42)20-43-21-25)18-39(35)47-37-13-12-32-31(5-3-6-34(32)37)33-4-1-2-7-36(33)41/h1-7,9,11,14,16-18,20-21,29,37,44-45H,8,10,12-13,15,22-23H2/t29-,37-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA... |
US Patent US10639284 (2020)
BindingDB Entry DOI: 10.7270/Q25Q5043 |
More data for this
Ligand-Target Pair | |