Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50274891
((Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazoli...)Show SMILES SC1=NC(=O)C(S1)=Cc1ccc2ccccc2c1 |w:7.8,t:1| Show InChI InChI=1S/C14H9NOS2/c16-13-12(18-14(17)15-13)8-9-5-6-10-3-1-2-4-11(10)7-9/h1-8H,(H,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assay |
Bioorg Med Chem 25: 2657-2665 (2017)
Article DOI: 10.1016/j.bmc.2017.02.056 BindingDB Entry DOI: 10.7270/Q2CV4M5V |
More data for this Ligand-Target Pair | |
Arylamine N-acetyltransferase 2
(Mus musculus) | BDBM50274891
((Z)-5-(Naphthalen-2'-ylmethylene)-2-thioxothiazoli...)Show SMILES SC1=NC(=O)C(S1)=Cc1ccc2ccccc2c1 |w:7.8,t:1| Show InChI InChI=1S/C14H9NOS2/c16-13-12(18-14(17)15-13)8-9-5-6-10-3-1-2-4-11(10)7-9/h1-8H,(H,15,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method |
Bioorg Med Chem 17: 905-18 (2009)
Article DOI: 10.1016/j.bmc.2008.11.032 BindingDB Entry DOI: 10.7270/Q2PZ58Q3 |
More data for this Ligand-Target Pair | |