Compile Data Set for Download or QSAR

Found 417 hits Enz. Inhib. hit(s) with Target = 'Ataxin-2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ataxin-2 (Homo sapiens (Human))	BDBM258501 (US10633384, Example 1.23 | US9493486, 1.23) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)OCc1ccc(OC(F)(F)F)cc1F Show InChI InChI=1S/C23H23F4N3O6S/c24-19-11-17(36-23(25,26)27)4-1-16(19)12-35-21(32)29-9-7-22(8-10-29)13-30(14-22)20(31)15-2-5-18(6-3-15)37(28,33)34/h1-6,11H,7-10,12-14H2,(H2,28,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258574 (US10633384, Example 12.36 | US9493486, 12.36) Show SMILES Fc1cc(ccc1COC(=O)N1CCC2(CN(C2)C(=O)C2CCc3[nH]nnc3C2)CC1)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258575 (US10633384, Example 12.37 | US9493486, 12.37) Show SMILES Cc1cc(OC(F)(F)F)ccc1COC(=O)N1CCC2(CN(C2)C(=O)C2CCc3[nH]nnc3C2)CC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258580 (US10633384, Example 12.42 | US9493486, 12.42) Show SMILES Fc1cc(OC(F)(F)F)ccc1COC(=O)N1CCC2(CN(C2)C(=O)C2CCc3[nH]nnc3C2)CC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258581 (US10633384, Example 12.43 | US9493486, 12.43) Show SMILES FC(F)(F)Oc1ccc(COC(=O)N2CCC3(CN(C3)C(=O)C3CCc4[nH]nnc4C3)CC2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258585 (US10633384, 13.01 | US9493486, 13.01) Show SMILES Fc1cc(OC(F)(F)F)ccc1COC(=O)N1CCC2(CN(C2)C(=O)N2CCc3[nH]nnc3C2)CC1 Show InChI InChI=1S/C22H24F4N6O4/c23-16-9-15(36-22(24,25)26)2-1-14(16)11-35-20(34)30-7-4-21(5-8-30)12-32(13-21)19(33)31-6-3-17-18(10-31)28-29-27-17/h1-2,9H,3-8,10-13H2,(H,27,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM440743 ((?)-2-Fluoro-4-(trifluoromethoxy)benzyl 2-(4,5,6,7...) Show SMILES Fc1cc(OC(F)(F)F)ccc1COC(=O)N1CCC2(CN(C2)C(=O)[C@H]2CCc3[nH]nnc3C2)CC1.Fc1cc(OC(F)(F)F)ccc1COC(=O)N1CCC2(CN(C2)C(=O)[C@@H]2CCc3[nH]nnc3C2)CC1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442737 (4-[5-[2-cyclopyropyl-6-[(1- | US10647719, Example ...) Show SMILES NS(=O)(=O)c1ccc(C(=O)N2CC3=C(CN(C3)C(=O)c3cc(OCC4CCOCC4)nc(c3)C3CC3)C2)c(F)c1F |t:12| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442707 (US10647719, Example 1.18 | [6-chloro-3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1ccc(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(cc1F)S(N)(=O)=O |c:21| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442712 (US10647719, Example 1.23 | [6-chloro-3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1ccc(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1c(F)cc(cc1F)S(N)(=O)=O |c:21| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442717 (BDBM442732 | US10647719, Example 1.28 | [3-(2,2-di...) Show SMILES CC(C)(C)C(=O)Nc1cc(cnc1COC(=O)N1CCC2=C(CCN(C2)C(=O)c2ccc(cc2F)S(N)(=O)=O)C1)C(F)(F)F |t:21| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442718 (US10647719, Example 2.00) Show SMILES CC(C)(C)C(=O)Nc1cc(C#N)c(Cl)cc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(cn1)S(N)(=O)=O |c:23| Show InChI InChI=1S/C26H27ClN6O6S/c1-26(2,3)24(35)31-22-7-15(8-28)20(27)6-16(22)14-39-25(36)33-12-17-10-32(11-18(17)13-33)23(34)21-5-4-19(9-30-21)40(29,37)38/h4-7,9H,10-14H2,1-3H3,(H,31,35)(H2,29,37,38)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM241106 (US9409895, 17 | US9630945, 17) Show SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)c1 Show InChI InChI=1S/C19H23Cl2N5O3/c20-14-8-13(9-15(21)10-14)12-29-19(28)26-6-4-16(5-7-26)23-18(27)3-1-2-17-11-22-25-24-17/h8-11,16H,1-7,12H2,(H,23,27)(H,22,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258579 (US10633384, Example 12.41 | US9493486, 12.41) Show SMILES Fc1cc(OC(F)(F)F)ccc1COC(=O)N1CC2(C1)CCN(CC2)C(=O)C1CCc2[nH]nnc2C1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442709 (US10647719, Example 1.20 | [6-chloro-3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1ccc(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1cc(F)c(cc1F)S(N)(=O)=O |c:21| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442711 (US10647719, Example 1.22 | [6-chloro-3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1ccc(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(c(F)c1F)S(N)(=O)=O |c:21| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM323247 (3,5-Dichlorobenzyl 4-(4-(2-oxo-2,3-dihydrothiazol-...) Show SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]c(=O)s2)c1 Show InChI InChI=1S/C20H23Cl2N3O4S/c21-14-8-13(9-15(22)10-14)12-29-20(28)25-6-4-16(5-7-25)24-18(26)3-1-2-17-11-23-19(27)30-17/h8-11,16H,1-7,12H2,(H,23,27)(H,24,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442736 (4-[5-[2-cyclopropyl-6-(oxan-4- | US10647719, Examp...) Show SMILES CC(C)(C)C(=O)Nc1cc(cnc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ncc(cc1F)S(N)(=O)=O)C(F)(F)F |c:20| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442735 (US10647719, Example 1.32 | [3-(2,2-dimethylpropano...) Show SMILES CC(C)(C)C(=O)Nc1cc(Cl)c(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1c(F)cc(cc1F)S(N)(=O)=O |c:22| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258576 (US10633384, Example 12.38 | US9493486, 12.38) Show SMILES Fc1cc(OCC(F)(F)F)ccc1COC(=O)N1CCC2(CN(C2)C(=O)C2CCc3nn[nH]c3C2)CC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258578 (US10633384, Example 12.40 | US9493486, 12.40) Show SMILES Fc1cc(COC(=O)N2CCC3(CN(C3)C(=O)C3CCc4nn[nH]c4C3)CC2)ccc1OCC(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM241108 (US9409895, 19 | US9630945, 19) Show SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CC2)NC(=O)CCc2c[nH]nn2)c1 Show InChI InChI=1S/C18H21Cl2N5O3/c19-13-7-12(8-14(20)9-13)11-28-18(27)25-5-3-15(4-6-25)22-17(26)2-1-16-10-21-24-23-16/h7-10,15H,1-6,11H2,(H,22,26)(H,21,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM241153 (US9409895, 63 | US9630945, 63) Show SMILES FC(F)(F)c1cc(Br)cc(COC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)c1 Show InChI InChI=1S/C20H23BrF3N5O3/c21-15-9-13(8-14(10-15)20(22,23)24)12-32-19(31)29-6-4-16(5-7-29)26-18(30)3-1-2-17-11-25-28-27-17/h8-11,16H,1-7,12H2,(H,26,30)(H,25,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352285 (CHEM-US-00050 | US9802944, Example 1.13) Show SMILES [H][C@@]12CN(C[C@@]1([H])CN(C2)C(=O)c1cc(OCC2CCOCC2)nc(c1)C1CC1)C(=O)CCc1cnn[nH]1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352340 (US11098048, Example 2.01 | US9802944, Example 2.01) Show SMILES O=C(N1C[C@H]2CN(C[C@@H]2C1)C(=O)c1cc(OCC2CCOCC2)nc(c1)C1CC1)c1ccc2[nH]nnc2c1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352271 (US9802944, Example 1) Show SMILES NS(=O)(=O)c1ccc(cn1)C(=O)N1C[C@H]2CN(C[C@@H]2C1)C(=O)c1cnc(OC2CCOCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C26H31N5O6S/c27-38(34,35)23-4-3-17(10-28-23)25(32)30-12-19-14-31(15-20(19)13-30)26(33)18-9-22(16-1-2-16)24(29-11-18)37-21-5-7-36-8-6-21/h3-4,9-11,16,19-21H,1-2,5-8,12-15H2,(H2,27,34,35)/t19-,20-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...				US Patent US10654857 (2020) BindingDB Entry DOI: 10.7270/Q2NK3J1K
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352339 (4-((3aR,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1C[C@H]2CN(C[C@H]2C1)C(=O)c1cnc(OC2CCOCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C27H32N4O6S/c28-38(34,35)23-5-3-18(4-6-23)26(32)30-13-20-15-31(16-21(20)14-30)27(33)19-11-24(17-1-2-17)25(29-12-19)37-22-7-9-36-10-8-22/h3-6,11-12,17,20-22H,1-2,7-10,13-16H2,(H2,28,34,35)/t20-,21+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...				US Patent US10654857 (2020) BindingDB Entry DOI: 10.7270/Q2NK3J1K
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352339 (4-((3aR,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1C[C@H]2CN(C[C@H]2C1)C(=O)c1cnc(OC2CCOCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C27H32N4O6S/c28-38(34,35)23-5-3-18(4-6-23)26(32)30-13-20-15-31(16-21(20)14-30)27(33)19-11-24(17-1-2-17)25(29-12-19)37-22-7-9-36-10-8-22/h3-6,11-12,17,20-22H,1-2,7-10,13-16H2,(H2,28,34,35)/t20-,21+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...				US Patent US10654857 (2020) BindingDB Entry DOI: 10.7270/Q2NK3J1K
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258584 (US10633384, Example 13 | US9493486, 13) Show SMILES FC(F)(F)Oc1ccc(COC(=O)N2CCC3(CN(C3)C(=O)N3CCc4[nH]nnc4C3)CC2)cc1 Show InChI InChI=1S/C22H25F3N6O4/c23-22(24,25)35-16-3-1-15(2-4-16)12-34-20(33)29-9-6-21(7-10-29)13-31(14-21)19(32)30-8-5-17-18(11-30)27-28-26-17/h1-4H,5-14H2,(H,26,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442710 (US10647719, Example 1.21 | [6-chloro-3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1ccc(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(c(F)c1)S(N)(=O)=O |c:21| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442715 (US10647719, Example 1.26 | [5-cyano-3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1cc(cnc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(c(F)c1F)S(N)(=O)=O)C#N |c:20| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352353 (((3aR,6aR)-hexahydropyrrolo[3,4- | US9802944, Exam...) Show SMILES [H][C@@]12CN(C[C@@]1([H])CN(C2)C(=O)c1cc(OCC2CCOCC2)nc(c1)C1CC1)C(=O)[C@@H]1CCc2[nH]nnc2C1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442741 (US10647719, Example 4.01 | [3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1cc2ccccc2nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(cc1F)S(N)(=O)=O |c:25| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442740 (US10647719, Example 4.00) Show SMILES Cc1nnn(Cc2cc(ccc2CCC(=O)N2CC3=C(C2)CN(C3)C(=O)c2ncc(cc2F)S(N)(=O)=O)C(F)(F)F)n1 |c:19| Show InChI InChI=1S/C25H24F4N8O4S/c1-14-32-34-37(33-14)13-16-6-19(25(27,28)29)4-2-15(16)3-5-22(38)35-9-17-11-36(12-18(17)10-35)24(39)23-21(26)7-20(8-31-23)42(30,40)41/h2,4,6-8H,3,5,9-13H2,1H3,(H2,30,40,41)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM241109 (US9409895, 20 | US9630945, 20) Show SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CC2)NC(=O)CCCCc2c[nH]nn2)c1 Show InChI InChI=1S/C20H25Cl2N5O3/c21-15-9-14(10-16(22)11-15)13-30-20(29)27-7-5-17(6-8-27)24-19(28)4-2-1-3-18-12-23-26-25-18/h9-12,17H,1-8,13H2,(H,24,28)(H,23,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM241156 (US9409895, 66 | US9630945, 66) Show SMILES FC(F)(F)c1cc(COC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)cc(c1)C#N Show InChI InChI=1S/C21H23F3N6O3/c22-21(23,24)16-9-14(11-25)8-15(10-16)13-33-20(32)30-6-4-17(5-7-30)27-19(31)3-1-2-18-12-26-29-28-18/h8-10,12,17H,1-7,13H2,(H,27,31)(H,26,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352316 (CHEM-US-00055 | US9802944, Example 1.18) Show SMILES [H][C@]12CN(C[C@]1([H])CN(C2)C(=O)c1ccc(cc1F)S(N)(=O)=O)C(=O)c1cc(OCC2CCOCC2)cc(c1)C1CC1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352271 (US9802944, Example 1) Show SMILES NS(=O)(=O)c1ccc(cn1)C(=O)N1C[C@H]2CN(C[C@@H]2C1)C(=O)c1cnc(OC2CCOCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C26H31N5O6S/c27-38(34,35)23-4-3-17(10-28-23)25(32)30-12-19-14-31(15-20(19)13-30)26(33)18-9-22(16-1-2-16)24(29-11-18)37-21-5-7-36-8-6-21/h3-4,9-11,16,19-21H,1-2,5-8,12-15H2,(H2,27,34,35)/t19-,20-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...				US Patent US10654857 (2020) BindingDB Entry DOI: 10.7270/Q2NK3J1K
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442706 (US10647719, Example 1.17 | [3-(2,2-dimethylpropano...) Show SMILES Cc1ccc(NC(=O)C(C)(C)C)c(COC(=O)N2CC3=C(C2)CN(C3)C(=O)c2ccc(cc2F)S(N)(=O)=O)n1 |c:19| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442708 (US10647719, Example 1.19 | [3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1cccnc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(cc1F)S(N)(=O)=O |c:20| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM241157 (US9409895, 67 | US9630945, 67) Show SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CC2)NC(=O)CCCCCc2c[nH]nn2)c1 Show InChI InChI=1S/C21H27Cl2N5O3/c22-16-10-15(11-17(23)12-16)14-31-21(30)28-8-6-18(7-9-28)25-20(29)5-3-1-2-4-19-13-24-27-26-19/h10-13,18H,1-9,14H2,(H,25,29)(H,24,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM442733 (US10647719, Example 1.30 | [5,6-dichloro-3-(2,2-) Show SMILES CC(C)(C)C(=O)Nc1cc(Cl)c(Cl)nc1COC(=O)N1CC2=C(C1)CN(C2)C(=O)c1ccc(cc1F)S(N)(=O)=O |c:22| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				US Patent US10647719 (2020) BindingDB Entry DOI: 10.7270/Q2V98C4V
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM258573 (US10633384, Example 12.35 | US9493486, 12.35) Show SMILES FC(F)(F)c1ccc(COC(=O)N2CCC3(CN(C3)C(=O)C3CCC4NN=NC4C3)CC2)cc1 |c:27| Show InChI InChI=1S/C23H28F3N5O3/c24-23(25,26)17-4-1-15(2-5-17)12-34-21(33)30-9-7-22(8-10-30)13-31(14-22)20(32)16-3-6-18-19(11-16)28-29-27-18/h1-2,4-5,16,18-19H,3,6-14H2,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US10633384 (2020) BindingDB Entry DOI: 10.7270/Q2K077BX
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352349 (US11098048, Example 2.06 | US9802944, Example 2.06) Show SMILES O=C(N1C[C@H]2CN(C[C@@H]2C1)C(=O)c1cnc(OC2CCCOC2)c(c1)C1CC1)c1ccc2[nH]nnc2c1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352339 (4-((3aR,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyr...) Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1C[C@H]2CN(C[C@H]2C1)C(=O)c1cnc(OC2CCOCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C27H32N4O6S/c28-38(34,35)23-5-3-18(4-6-23)26(32)30-13-20-15-31(16-21(20)14-30)27(33)19-11-24(17-1-2-17)25(29-12-19)37-22-7-9-36-10-8-22/h3-6,11-12,17,20-22H,1-2,7-10,13-16H2,(H2,28,34,35)/t20-,21+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...				US Patent US10654857 (2020) BindingDB Entry DOI: 10.7270/Q2NK3J1K
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM241152 (US9409895, 62 | US9630945, 62) Show SMILES Cc1cc(COC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)cc(c1)C(F)(F)F Show InChI InChI=1S/C21H26F3N5O3/c1-14-9-15(11-16(10-14)21(22,23)24)13-32-20(31)29-7-5-17(6-8-29)26-19(30)4-2-3-18-12-25-28-27-18/h9-12,17H,2-8,13H2,1H3,(H,26,30)(H,25,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM323244 (3-Cyano-5-(trifluoromethoxy)benzyl 4-(4-(1H-1,2,3-...) Show SMILES FC(F)(F)Oc1cc(COC(=O)N2CCC(CC2)NC(=O)CCCc2c[nH]nn2)cc(c1)C#N Show InChI InChI=1S/C21H23F3N6O4/c22-21(23,24)34-18-9-14(11-25)8-15(10-18)13-33-20(32)30-6-4-16(5-7-30)27-19(31)3-1-2-17-12-26-29-28-17/h8-10,12,16H,1-7,13H2,(H,27,31)(H,26,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US9630945 (2017) BindingDB Entry DOI: 10.7270/Q25Q4Z5R
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352280 (CHEM-US-00046 | US9802944, Example 1.09) Show SMILES [H][C@@]12CN(C[C@]1([H])CCN(CC2)C(=O)c1cc(OCC2CCOCC2)nc(c1)C1CC1)C(=O)c1ccc(cc1)S(N)(=O)=O |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352332 (BDBM352333 | CHEM-US-00058 | US9802944, Example 1....) Show SMILES [H][C@@]12CN(C[C@]1([H])CCN(CC2)C(=O)c1cc(OCC2CCOCC2)nc(c1)C1CC1)C(=O)CCc1c[nH]c(=O)o1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair
Ataxin-2 (Homo sapiens (Human))	BDBM352366 (US11098048, Example 2.23 | US9802944, Example 2.23) Show SMILES CN(C)c1cc(cc(OCC2CCOCC2)n1)C(=O)N1C[C@@H]2CN(C[C@H]2C1)C(=O)c1ccc2[nH]nnc2c1 |r| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				US Patent US9802944 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z9M
					More data for this Ligand-Target Pair

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