Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Dynein light chain 2, cytoplasmic'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynein light chain 2, cytoplasmic (Human)	BDBM528572 (US11192893, Example 12) Show SMILES Clc1ccc(cc1)C1(CC1)c1nn2c([nH]c3ccc(Br)cc3c2=O)c1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...				Citation and Details BindingDB Entry DOI: 10.7270/Q22J6G18
					More data for this Ligand-Target Pair
Dynein light chain 2, cytoplasmic (Human)	BDBM528573 (US11192893, Example 27) Show SMILES Clc1ccc(cc1)C1CCC(CC1)c1nn2c([nH]c3ccccc3c2=O)c1C#N |(9.24,.55,;7.7,.55,;6.93,-.79,;5.39,-.79,;4.62,.55,;5.39,1.88,;6.93,1.88,;3.08,.55,;2.31,-.79,;.77,-.79,;0,.55,;.77,1.88,;2.31,1.88,;-1.54,.55,;-2.44,1.79,;-3.91,1.32,;-3.91,-.22,;-5.24,-.99,;-6.57,-.22,;-7.91,-.99,;-9.24,-.22,;-9.24,1.32,;-7.91,2.09,;-6.57,1.32,;-5.24,2.09,;-5.24,3.63,;-2.44,-.7,;-1.97,-2.16,;-1.49,-3.63,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...				Citation and Details BindingDB Entry DOI: 10.7270/Q22J6G18
					More data for this Ligand-Target Pair
Dynein light chain 2, cytoplasmic (Human)	BDBM528576 (US11192893, Example 31) Show SMILES Clc1ccc(cc1)C1(CC1)c1nn2c([nH]c3ccccc3c2=O)c1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...				Citation and Details BindingDB Entry DOI: 10.7270/Q22J6G18
					More data for this Ligand-Target Pair
Dynein light chain 2, cytoplasmic (Human)	BDBM528579 (US11192893, Example 29) Show SMILES Clc1ccc(OCCCc2nn3c([nH]c4ccccc4c3=O)c2C#N)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...				Citation and Details BindingDB Entry DOI: 10.7270/Q22J6G18
					More data for this Ligand-Target Pair
Dynein light chain 2, cytoplasmic (Human)	BDBM528571 (US11192893, Example 5) Show SMILES Clc1ccc(cc1)C1(CC1)c1nn2c([nH]c(=O)c3cc(I)ccc23)c1C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...				Citation and Details BindingDB Entry DOI: 10.7270/Q22J6G18
					More data for this Ligand-Target Pair
Dynein light chain 2, cytoplasmic (Human)	BDBM528570 (US11192893, Example 4) Show SMILES FC(F)(F)c1ccc2c(c1)c(=O)[nH]c1c(C#N)c(nn21)C1(CC1)c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...				Citation and Details BindingDB Entry DOI: 10.7270/Q22J6G18
					More data for this Ligand-Target Pair