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Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with Target = 'Formyl peptide receptor 2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Formyl peptide receptor 2


(Mus musculus)
BDBM50559829
PNG
(CHEMBL4784510)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.5n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse FPR2 expressed in CHO cells assessed as reduction cAMP accumulation incubated for 1 hr by TR-FRET assay


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50559829
PNG
(CHEMBL4784510)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1n/an/an/an/a


TBA

Assay Description
Agonist activity at FPR2 in mouse peritoneal macrophages assessed as inhibition of stimulated phagocytosis preincubated for 15 mins followed by FITC ...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50559821
PNG
(CHEMBL4781596)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.5n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50559829
PNG
(CHEMBL4784510)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.40n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50559829
PNG
(CHEMBL4784510)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
n/an/an/an/a 384n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50559838
PNG
(CHEMBL4790836)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)c(O)c2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.630n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50559840
PNG
(CHEMBL4760897)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)s2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.40n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50186957
PNG
(1-(3-tert-butyl-2-methyl-5-oxo-1-phenyl-2,5-dihydr...)
Show SMILES Cn1c(c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n1-c1ccccc1)C(C)(C)C
Show InChI InChI=1S/C21H23ClN4O2/c1-21(2,3)18-17(24-20(28)23-15-12-10-14(22)11-13-15)19(27)26(25(18)4)16-8-6-5-7-9-16/h5-13H,1-4H3,(H2,23,24,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/an/an/a 50n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Formyl peptide receptor 2


(Mus musculus)
BDBM50559835
PNG
(CHEMBL4762030)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(F)c2)c(F)c1 |r|
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 8.5n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair