Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50110121![]() (3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM, MRL Rome Curated by ChEMBL | Assay Description Inhibition of hepatitis C virus (HCV) NS3/NS4A serine protease | Bioorg Med Chem Lett 12: 701-4 (2002) BindingDB Entry DOI: 10.7270/Q28P5ZSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50110121![]() (3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM, MRL Rome Curated by ChEMBL | Assay Description Inhibitory activity against hepatitis C virus (HCV) NS3/NS4A serine protease | Bioorg Med Chem Lett 12: 705-8 (2002) BindingDB Entry DOI: 10.7270/Q24X572V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573891![]() (A-1282576 | A-1282576.0 | A-12825760 | ABT-493 | G...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50458698![]() (CHEMBL4203709) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Massachusetts Medical School Curated by ChEMBL | Assay Description Inhibition of wild type HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) using Ac-DE-Dap(QXL 520)-EE-Abu-psi-[COO]AS-C(5-FAMsp... | ACS Med Chem Lett 9: 691-696 (2018) Article DOI: 10.1021/acsmedchemlett.8b00150 BindingDB Entry DOI: 10.7270/Q29C7125 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50485492![]() (Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573903![]() (CHEMBL4852970) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573887![]() (CHEMBL4879085) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573891![]() (A-1282576 | A-1282576.0 | A-12825760 | ABT-493 | G...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-3a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50110117![]() (4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM, MRL Rome Curated by ChEMBL | Assay Description Inhibition of hepatitis C virus (HCV) NS3/NS4A serine protease | Bioorg Med Chem Lett 12: 701-4 (2002) BindingDB Entry DOI: 10.7270/Q28P5ZSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573886![]() (CHEMBL4848452) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50110117![]() (4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{3...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM, MRL Rome Curated by ChEMBL | Assay Description Inhibitory activity against hepatitis C virus (HCV) NS3/NS4A serine protease | Bioorg Med Chem Lett 12: 705-8 (2002) BindingDB Entry DOI: 10.7270/Q24X572V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573919![]() (CHEMBL4854503) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573914![]() (CHEMBL4875061) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573915![]() (CHEMBL4864092) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50458698![]() (CHEMBL4203709) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Massachusetts Medical School Curated by ChEMBL | Assay Description Inhibition of HCV genotype 1a NS3/4A protease R155K mutant expressed in Escherichia coli BL21(DE3) using Ac-DE-Dap(QXL 520)-EE-Abu-psi-[COO]AS-C(5-FA... | ACS Med Chem Lett 9: 691-696 (2018) Article DOI: 10.1021/acsmedchemlett.8b00150 BindingDB Entry DOI: 10.7270/Q29C7125 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573881![]() (CHEMBL4848772) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573902![]() (CHEMBL4860811) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573884![]() (CHEMBL4863541) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573883![]() (CHEMBL4863232) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573880![]() (CHEMBL4847539) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573888![]() (CHEMBL4849669) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573916![]() (CHEMBL4846475) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573917![]() (CHEMBL4863621) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573913![]() (CHEMBL4876997) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573890![]() (CHEMBL4856675) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50110122![]() ((S)-4-((S)-2-Acetylamino-3-carboxy-propionylamino)...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM, MRL Rome Curated by ChEMBL | Assay Description Inhibition of hepatitis C virus (HCV) NS3/NS4A serine protease | Bioorg Med Chem Lett 12: 701-4 (2002) BindingDB Entry DOI: 10.7270/Q28P5ZSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573911![]() (CHEMBL4852548) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573912![]() (CHEMBL4871600) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573885![]() (CHEMBL4859365) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573910![]() (CHEMBL4866052) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM103841![]() (5172-mcP1P3) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Massachusetts Medical School Curated by ChEMBL | Assay Description Inhibition of wild type HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) using Ac-DE-Dap(QXL 520)-EE-Abu-psi-[COO]AS-C(5-FAMsp... | ACS Med Chem Lett 9: 691-696 (2018) Article DOI: 10.1021/acsmedchemlett.8b00150 BindingDB Entry DOI: 10.7270/Q29C7125 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573908![]() (CHEMBL4872547) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50110120![]() (3-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM, MRL Rome Curated by ChEMBL | Assay Description Inhibition of hepatitis C virus (HCV) NS3/NS4A serine protease | Bioorg Med Chem Lett 12: 701-4 (2002) BindingDB Entry DOI: 10.7270/Q28P5ZSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573909![]() (CHEMBL4863145) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573900![]() (CHEMBL4873577) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50458703![]() (CHEMBL4210043) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Massachusetts Medical School Curated by ChEMBL | Assay Description Inhibition of HCV genotype 1a NS3/4A protease R155K mutant expressed in Escherichia coli BL21(DE3) using Ac-DE-Dap(QXL 520)-EE-Abu-psi-[COO]AS-C(5-FA... | ACS Med Chem Lett 9: 691-696 (2018) Article DOI: 10.1021/acsmedchemlett.8b00150 BindingDB Entry DOI: 10.7270/Q29C7125 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573889![]() (CHEMBL4847677) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573879![]() (CHEMBL4873756) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573893![]() (CHEMBL4854781) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573899![]() (CHEMBL4852637) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573923![]() (CHEMBL4861087) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573924![]() (CHEMBL4848226) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573920![]() (CHEMBL4876441) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM103841![]() (5172-mcP1P3) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Massachusetts Medical School Curated by ChEMBL | Assay Description Inhibition of HCV genotype 1a NS3/4A protease R155K mutant expressed in Escherichia coli BL21(DE3) using Ac-DE-Dap(QXL 520)-EE-Abu-psi-[COO]AS-C(5-FA... | ACS Med Chem Lett 9: 691-696 (2018) Article DOI: 10.1021/acsmedchemlett.8b00150 BindingDB Entry DOI: 10.7270/Q29C7125 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573882![]() (CHEMBL4873674) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573925![]() (CHEMBL4871632) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573878![]() (CHEMBL4870588) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50573897![]() (CHEMBL4851215) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of HCV GT-1a NS3/4a protease using Ac-DE-D(Edans)-EE-Abu-c-[COO]-AS-K(Dabcy1)-NH2 preincubated for 1 hr followed by substrate addition | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00554 BindingDB Entry DOI: 10.7270/Q2377DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50458701![]() (CHEMBL4218289) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Massachusetts Medical School Curated by ChEMBL | Assay Description Inhibition of wild type HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) using Ac-DE-Dap(QXL 520)-EE-Abu-psi-[COO]AS-C(5-FAMsp... | ACS Med Chem Lett 9: 691-696 (2018) Article DOI: 10.1021/acsmedchemlett.8b00150 BindingDB Entry DOI: 10.7270/Q29C7125 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein/Non-structural protein 4A (Hepatitis C virus) | BDBM50458705![]() (CHEMBL4208020) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Massachusetts Medical School Curated by ChEMBL | Assay Description Inhibition of HCV genotype 1a NS3/4A protease R155K mutant expressed in Escherichia coli BL21(DE3) using Ac-DE-Dap(QXL 520)-EE-Abu-psi-[COO]AS-C(5-FA... | ACS Med Chem Lett 9: 691-696 (2018) Article DOI: 10.1021/acsmedchemlett.8b00150 BindingDB Entry DOI: 10.7270/Q29C7125 | |||||||||||
More data for this Ligand-Target Pair |
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