Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015743![]() (Acetic acid 3-[1-(3,6-dihydro-2H-pyridin-1-yl)-cyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015738![]() (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015734![]() (1-(1-Thiophen-2-yl-cyclohexyl)-1,2,3,6-tetrahydro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015741![]() (1-[1-(3-Methoxy-phenyl)-cyclohexyl]-1,2,3,6-tetrah...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015732![]() (1-(1-Phenyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015733![]() (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM83449![]() (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum. | J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015735![]() (1-(1-m-Tolyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM83449![]() (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047 | J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015744![]() (1-[1-(3-Methoxymethoxy-phenyl)-cyclohexyl]-1,2,3,6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015740![]() (1-[1-(3-Vinyl-phenyl)-cyclohexyl]-1,2,3,6-tetrahyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50018933![]() (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum. | J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015731![]() (1-[1-(3-Methylsulfanyl-phenyl)-cyclohexyl]-1,2,3,6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 231 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015736![]() (1-[1-(3-Fluoro-phenyl)-cyclohexyl]-1,2,3,6-tetrahy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 281 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015739![]() (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 324 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50368882![]() (CHEMBL147585 | SK&F-10047 | SK-10047) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M | J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50368882![]() (CHEMBL147585 | SK&F-10047 | SK-10047) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Binding affinity of compound was tested on Phencyclidine binding assay. | J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015730![]() (1-[1-(3-Trifluoromethyl-phenyl)-cyclohexyl]-1,2,3,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 422 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM83449![]() (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047 | J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015742![]() (1-[1-(3-[1,3]Dioxolan-2-yl-phenyl)-cyclohexyl]-1,2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 601 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50405724![]() (CHEMBL1169565) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCP | J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50038169![]() ((3R,4R)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor | J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50405723![]() (CHEMBL1169564) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCP | J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50062599![]() (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Compound with the N-methyl-D-aspartate glutamate receptor blocking activity | J Med Chem 42: 1481-500 (1999) Article DOI: 10.1021/jm9805034 BindingDB Entry DOI: 10.7270/Q2HX1DCV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015745![]() (1-[1-(3-Benzyloxy-phenyl)-cyclohexyl]-1,2,3,6-tetr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 733 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50038175![]() ((3R,4R)-3-Amino-1,4-dihydroxy-pyrrolidin-2-one | C...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor | J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM213888![]() (1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | >800 | >-34.8 | >3.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Copenhagen | Assay Description Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl... | J Biol Chem 288: 33124-35 (2013) Article DOI: 10.1074/jbc.M113.480210 BindingDB Entry DOI: 10.7270/Q2MG7NB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50018932![]() (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum. | J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50288367![]() (3-(2,3-Dioxo-7-pyrrol-1-yl-6-trifluoromethyl-3,4-d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for binding affinity against glycine site of NMDA receptor using [3H]-glycine as a radioligand. | Bioorg Med Chem Lett 6: 2887-2892 (1996) Article DOI: 10.1016/S0960-894X(96)00534-3 BindingDB Entry DOI: 10.7270/Q23N23BK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50048875![]() (CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M | J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50018929![]() (3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum. | J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50018929![]() (3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Inhibition activity against binding of phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum. | J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50038159![]() ((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor | J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50405723![]() (CHEMBL1169564) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047 | J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50405724![]() (CHEMBL1169565) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047 | J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50018931![]() (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum. | J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50038157![]() (6-Hydroxy-2,6-diaza-bicyclo[3.2.1]octan-7-one | CH...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor | J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50048867![]() (1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M | J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50018930![]() (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum. | J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50007314![]() (CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 6.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was tested for the inhibitory concentration against phencyclidine by using [3H]-TCP as radioligand at PCP receptor in guinea pig brain | J Med Chem 34: 3058-65 (1991) BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50288358![]() ((2,3-Dioxo-7-pyrrol-1-yl-6-trifluoromethyl-3,4-dih...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for binding affinity against glycine site of NMDA receptor using [3H]-glycine as a radioligand. | Bioorg Med Chem Lett 6: 2887-2892 (1996) Article DOI: 10.1016/S0960-894X(96)00534-3 BindingDB Entry DOI: 10.7270/Q23N23BK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50048871![]() (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M | J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50048873![]() (1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M | J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50015737![]() (1-[1-(3,5-Dimethoxy-phenyl)-cyclohexyl]-1,2,3,6-te...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum. | J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50037480![]() ((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity against PCP receptor from guinea pig brain, using [3H]TCP as radioligand. | J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50064173![]() (1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain | J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50064175![]() (1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain | J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50064172![]() (1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain | J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50036764![]() (1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-2,4'-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain | J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM50064171![]() (1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain | J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q | |||||||||||
More data for this Ligand-Target Pair |
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