Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with Target = 'Hsp90 co-chaperone Cdc37'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279657 (US10035797, Compound 1 | US10428068, Compound 1 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3Br)nc12 Show InChI InChI=1S/C18H15BrN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279658 (US10035797, Compound 2 | US10428068, Compound 2 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3Cl)nc12 Show InChI InChI=1S/C18H15ClN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279664 (US10035797, Compound 3 | US10428068, Compound 3 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3I)nc12 Show InChI InChI=1S/C18H15IN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279695 (US10035797, Compound 34 | US10035797, Compound 37 ...) Show SMILES CC(C)(C)CNCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)nccc12 Show InChI InChI=1S/C20H24IN5O2S/c1-20(2,3)10-23-6-7-26-13-4-5-24-18(22)17(13)25-19(26)29-16-9-15-14(8-12(16)21)27-11-28-15/h4-5,8-9,23H,6-7,10-11H2,1-3H3,(H2,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279657 (US10035797, Compound 1 | US10428068, Compound 1 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3Br)nc12 Show InChI InChI=1S/C18H15BrN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279657 (US10035797, Compound 1 | US10428068, Compound 1 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3Br)nc12 Show InChI InChI=1S/C18H15BrN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279664 (US10035797, Compound 3 | US10428068, Compound 3 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3I)nc12 Show InChI InChI=1S/C18H15IN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279664 (US10035797, Compound 3 | US10428068, Compound 3 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3I)nc12 Show InChI InChI=1S/C18H15IN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279695 (US10035797, Compound 34 | US10035797, Compound 37 ...) Show SMILES CC(C)(C)CNCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)nccc12 Show InChI InChI=1S/C20H24IN5O2S/c1-20(2,3)10-23-6-7-26-13-4-5-24-18(22)17(13)25-19(26)29-16-9-15-14(8-12(16)21)27-11-28-15/h4-5,8-9,23H,6-7,10-11H2,1-3H3,(H2,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279695 (US10035797, Compound 34 | US10035797, Compound 37 ...) Show SMILES CC(C)(C)CNCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)nccc12 Show InChI InChI=1S/C20H24IN5O2S/c1-20(2,3)10-23-6-7-26-13-4-5-24-18(22)17(13)25-19(26)29-16-9-15-14(8-12(16)21)27-11-28-15/h4-5,8-9,23H,6-7,10-11H2,1-3H3,(H2,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279658 (US10035797, Compound 2 | US10428068, Compound 2 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3Cl)nc12 Show InChI InChI=1S/C18H15ClN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279658 (US10035797, Compound 2 | US10428068, Compound 2 | ...) Show SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3Cl)nc12 Show InChI InChI=1S/C18H15ClN4O2S/c1-2-3-4-7-23-12-5-6-21-17(20)16(12)22-18(23)26-15-9-14-13(8-11(15)19)24-10-25-14/h1,5-6,8-9H,3-4,7,10H2,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279682 (US10035797, Compound 19 | US10428068, Compound 19 ...) Show SMILES COc1ccc(C(C)=O)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C20H20N4O2S/c1-4-5-6-11-24-16-9-10-22-19(21)18(16)23-20(24)27-17-12-14(26-3)7-8-15(17)13(2)25/h1,7-10,12H,5-6,11H2,2-3H3,(H2,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279676 (US10035797, Compound 14 | US10428068, Compound 14 ...) Show SMILES COc1ccc(Cl)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17ClN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279675 (US10035797, Compound 13 | US10428068, Compound 13 ...) Show SMILES COc1ccc(Br)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17BrN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279673 (US10035797, Compound 12 | US10428068, Compound 12 ...) Show SMILES COc1ccc(I)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17IN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279682 (US10035797, Compound 19 | US10428068, Compound 19 ...) Show SMILES COc1ccc(C(C)=O)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C20H20N4O2S/c1-4-5-6-11-24-16-9-10-22-19(21)18(16)23-20(24)27-17-12-14(26-3)7-8-15(17)13(2)25/h1,7-10,12H,5-6,11H2,2-3H3,(H2,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279676 (US10035797, Compound 14 | US10428068, Compound 14 ...) Show SMILES COc1ccc(Cl)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17ClN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279675 (US10035797, Compound 13 | US10428068, Compound 13 ...) Show SMILES COc1ccc(Br)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17BrN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279673 (US10035797, Compound 12 | US10428068, Compound 12 ...) Show SMILES COc1ccc(I)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17IN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279682 (US10035797, Compound 19 | US10428068, Compound 19 ...) Show SMILES COc1ccc(C(C)=O)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C20H20N4O2S/c1-4-5-6-11-24-16-9-10-22-19(21)18(16)23-20(24)27-17-12-14(26-3)7-8-15(17)13(2)25/h1,7-10,12H,5-6,11H2,2-3H3,(H2,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279676 (US10035797, Compound 14 | US10428068, Compound 14 ...) Show SMILES COc1ccc(Cl)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17ClN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279675 (US10035797, Compound 13 | US10428068, Compound 13 ...) Show SMILES COc1ccc(Br)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17BrN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279673 (US10035797, Compound 12 | US10428068, Compound 12 ...) Show SMILES COc1ccc(I)c(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H17IN4OS/c1-3-4-5-10-23-14-8-9-21-17(20)16(14)22-18(23)25-15-11-12(24-2)6-7-13(15)19/h1,6-9,11H,4-5,10H2,2H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279672 (US10035797, Compound 11 | US10428068, Compound 11 ...) Show SMILES COc1cccc(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H18N4OS/c1-3-4-5-11-22-15-9-10-20-17(19)16(15)21-18(22)24-14-8-6-7-13(12-14)23-2/h1,6-10,12H,4-5,11H2,2H3,(H2,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279672 (US10035797, Compound 11 | US10428068, Compound 11 ...) Show SMILES COc1cccc(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H18N4OS/c1-3-4-5-11-22-15-9-10-20-17(19)16(15)21-18(22)24-14-8-6-7-13(12-14)23-2/h1,6-10,12H,4-5,11H2,2H3,(H2,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279680 (US10035797, Compound 17 | US10428068, Compound 17 ...) Show SMILES COc1ccc(c(Sc2nc3c(N)nccc3n2CCCC#C)c1)[N+]([O-])=O Show InChI InChI=1S/C18H17N5O3S/c1-3-4-5-10-22-14-8-9-20-17(19)16(14)21-18(22)27-15-11-12(26-2)6-7-13(15)23(24)25/h1,6-9,11H,4-5,10H2,2H3,(H2,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US9630965 (2017) BindingDB Entry DOI: 10.7270/Q2SF2Z85
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279672 (US10035797, Compound 11 | US10428068, Compound 11 ...) Show SMILES COc1cccc(Sc2nc3c(N)nccc3n2CCCC#C)c1 Show InChI InChI=1S/C18H18N4OS/c1-3-4-5-11-22-15-9-10-20-17(19)16(15)21-18(22)24-14-8-6-7-13(12-14)23-2/h1,6-10,12H,4-5,11H2,2H3,(H2,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279680 (US10035797, Compound 17 | US10428068, Compound 17 ...) Show SMILES COc1ccc(c(Sc2nc3c(N)nccc3n2CCCC#C)c1)[N+]([O-])=O Show InChI InChI=1S/C18H17N5O3S/c1-3-4-5-10-22-14-8-9-20-17(19)16(14)21-18(22)27-15-11-12(26-2)6-7-13(15)23(24)25/h1,6-9,11H,4-5,10H2,2H3,(H2,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN77VB
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM279680 (US10035797, Compound 17 | US10428068, Compound 17 ...) Show SMILES COc1ccc(c(Sc2nc3c(N)nccc3n2CCCC#C)c1)[N+]([O-])=O Show InChI InChI=1S/C18H17N5O3S/c1-3-4-5-10-22-14-8-9-20-17(19)16(14)21-18(22)27-15-11-12(26-2)6-7-13(15)23(24)25/h1,6-9,11H,4-5,10H2,2H3,(H2,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Curis, Inc. US Patent					Assay Description The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...				US Patent US10428068 (2019) BindingDB Entry DOI: 10.7270/Q2B56N4C
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406716 (US10336757, Compound PU-DZ14) Show SMILES CC(C)(C)CNCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C20H24FIN6O2/c1-20(2,3)9-24-4-5-28-15(25-16-17(23)26-19(21)27-18(16)28)7-11-6-13-14(8-12(11)22)30-10-29-13/h6,8,24H,4-5,7,9-10H2,1-3H3,(H2,23,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	23.5	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406717 (US10336757, Compound PU-DZ16) Show SMILES Nc1nc(F)nc2n(CCNCC3CC3)c(Cc3cc4OCOc4cc3I)nc12 Show InChI InChI=1S/C19H20FIN6O2/c20-19-25-17(22)16-18(26-19)27(4-3-23-8-10-1-2-10)15(24-16)6-11-5-13-14(7-12(11)21)29-9-28-13/h5,7,10,23H,1-4,6,8-9H2,(H2,22,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	35.6	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406718 (US10336757, Compound PU-DZ15) Show SMILES CCN(C)CCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C18H20FIN6O2/c1-3-25(2)4-5-26-14(22-15-16(21)23-18(19)24-17(15)26)7-10-6-12-13(8-11(10)20)28-9-27-12/h6,8H,3-5,7,9H2,1-2H3,(H2,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	166	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406719 (US10336757, Compound PU-DZ17) Show SMILES CC(C)N(C)CCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C19H22FIN6O2/c1-10(2)26(3)4-5-27-15(23-16-17(22)24-19(20)25-18(16)27)7-11-6-13-14(8-12(11)21)29-9-28-13/h6,8,10H,4-5,7,9H2,1-3H3,(H2,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	92.3	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406720 (US10336757, Compound PU-DZ18) Show SMILES CN(CCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12)CC#N Show InChI InChI=1S/C18H17FIN7O2/c1-26(3-2-21)4-5-27-14(23-15-16(22)24-18(19)25-17(15)27)7-10-6-12-13(8-11(10)20)29-9-28-12/h6,8H,3-5,7,9H2,1H3,(H2,22,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406701 (US10336757, Compound PU-HT70) Show SMILES CC(C)NCCCn1c(Cc2cc3OCOc3cc2C=C)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C21H25FN6O2/c1-4-13-8-15-16(30-11-29-15)9-14(13)10-17-25-18-19(23)26-21(22)27-20(18)28(17)7-5-6-24-12(2)3/h4,8-9,12,24H,1,5-7,10-11H2,2-3H3,(H2,23,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	147	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406700 (US10336757, Compound PU-DZ10) Show SMILES CC(C)NCCCn1c(Cc2cc3OCOc3cc2Br)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C19H22BrFN6O2/c1-10(2)23-4-3-5-27-15(24-16-17(22)25-19(21)26-18(16)27)7-11-6-13-14(8-12(11)20)29-9-28-13/h6,8,10,23H,3-5,7,9H2,1-2H3,(H2,22,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	193	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM50180301 (2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9...) Show SMILES CC(C)NCCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C19H22FIN6O2/c1-10(2)23-4-3-5-27-15(24-16-17(22)25-19(20)26-18(16)27)7-11-6-13-14(8-12(11)21)29-9-28-13/h6,8,10,23H,3-5,7,9H2,1-2H3,(H2,22,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	60.7	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM50180306 (8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISO...) Show SMILES CC(C)NCCCn1c(Sc2cc3OCOc3cc2Br)nc2c(N)ncnc12 Show InChI InChI=1S/C18H21BrN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	n/a	n/a	122	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406697 (US10336757, Compound PU-HT65) Show SMILES CC(C)NCCCn1c(Sc2cc3OCOc3cc2C=C)nc2c(N)ncnc12 Show InChI InChI=1S/C20H24N6O2S/c1-4-13-8-14-15(28-11-27-14)9-16(13)29-20-25-17-18(21)23-10-24-19(17)26(20)7-5-6-22-12(2)3/h4,8-10,12,22H,1,5-7,11H2,2-3H3,(H2,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	213	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM50180302 (8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isop...) Show SMILES CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12 Show InChI InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	30.8	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406709 (US10336757, Compound PU-BSI15) Show SMILES Nc1nc(F)nc2n(CCCN3CCCCC3)c(Cc3cc4OCOc4cc3I)nc12 Show InChI InChI=1S/C21H24FIN6O2/c22-21-26-19(24)18-20(27-21)29(8-4-7-28-5-2-1-3-6-28)17(25-18)10-13-9-15-16(11-14(13)23)31-12-30-15/h9,11H,1-8,10,12H2,(H2,24,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	68.2	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406708 (US10336757, Compound PU-BSI14) Show SMILES CCCN(CCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12)C1CC1 Show InChI InChI=1S/C22H26FIN6O2/c1-2-6-29(14-4-5-14)7-3-8-30-18(26-19-20(25)27-22(23)28-21(19)30)10-13-9-16-17(11-15(13)24)32-12-31-16/h9,11,14H,2-8,10,12H2,1H3,(H2,25,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	42.8	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406707 (US10336757, Compound PU-BSI7) Show SMILES CN(CCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12)CC=C Show InChI InChI=1S/C20H22FIN6O2/c1-3-5-27(2)6-4-7-28-16(24-17-18(23)25-20(21)26-19(17)28)9-12-8-14-15(10-13(12)22)30-11-29-14/h3,8,10H,1,4-7,9,11H2,2H3,(H2,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	44.5	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406706 (US10336757, Compound PU-BSI11) Show SMILES CN(CCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12)CC#C Show InChI InChI=1S/C20H20FIN6O2/c1-3-5-27(2)6-4-7-28-16(24-17-18(23)25-20(21)26-19(17)28)9-12-8-14-15(10-13(12)22)30-11-29-14/h1,8,10H,4-7,9,11H2,2H3,(H2,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406705 (US10336757, Compound PU-BSI6) Show SMILES CC(C)N(CCO)CCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C21H26FIN6O3/c1-12(2)28(6-7-30)4-3-5-29-17(25-18-19(24)26-21(22)27-20(18)29)9-13-8-15-16(10-14(13)23)32-11-31-15/h8,10,12,30H,3-7,9,11H2,1-2H3,(H2,24,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	60.8	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406704 (US10336757, Compound PU-BSI12) Show SMILES CC(C)N(C)CCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C20H24FIN6O2/c1-11(2)27(3)5-4-6-28-16(24-17-18(23)25-20(21)26-19(17)28)8-12-7-14-15(9-13(12)22)30-10-29-14/h7,9,11H,4-6,8,10H2,1-3H3,(H2,23,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	39.4	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406703 (US10336757, Compound PU-HT133) Show SMILES CCc1cc2OCOc2cc1Cc1nc2c(N)nc(F)nc2n1CCCNC(C)C Show InChI InChI=1S/C21H27FN6O2/c1-4-13-8-15-16(30-11-29-15)9-14(13)10-17-25-18-19(23)26-21(22)27-20(18)28(17)7-5-6-24-12(2)3/h8-9,12,24H,4-7,10-11H2,1-3H3,(H2,23,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	813	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406715 (US10336757, Compound PU-DZ13) Show SMILES CC(C)CNCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C19H22FIN6O2/c1-10(2)8-23-3-4-27-15(24-16-17(22)25-19(20)26-18(16)27)6-11-5-13-14(7-12(11)21)29-9-28-13/h5,7,10,23H,3-4,6,8-9H2,1-2H3,(H2,22,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	19.6	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair
Hsp90 co-chaperone Cdc37 (Homo sapiens (Human))	BDBM406714 (US10336757, Compound PU-DZ12) Show SMILES CC(C)NCCn1c(Cc2cc3OCOc3cc2I)nc2c(N)nc(F)nc12 Show InChI InChI=1S/C18H20FIN6O2/c1-9(2)22-3-4-26-14(23-15-16(21)24-18(19)25-17(15)26)6-10-5-12-13(7-11(10)20)28-8-27-12/h5,7,9,22H,3-4,6,8H2,1-2H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	219	n/a	n/a	n/a	n/a
Sloan-Kettering Institute for Cancer Research US Patent					Assay Description The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...				US Patent US10336757 (2019) BindingDB Entry DOI: 10.7270/Q2VT1VF6
					More data for this Ligand-Target Pair

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