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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hsp90 co-chaperone Cdc37' and Ligand = 'BDBM406703'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hsp90 co-chaperone Cdc37


(Homo sapiens (Human))		BDBM406703
PNG
(US10336757, Compound PU-HT133)
Show SMILES CCc1cc2OCOc2cc1Cc1nc2c(N)nc(F)nc2n1CCCNC(C)C
Show InChI InChI=1S/C21H27FN6O2/c1-4-13-8-15-16(30-11-29-15)9-14(13)10-17-25-18-19(23)26-21(22)27-20(18)28(17)7-5-6-24-12(2)3/h8-9,12,24H,4-7,10-11H2,1-3H3,(H2,23,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 813n/an/an/an/a



Sloan-Kettering Institute for Cancer Research

US Patent


Assay Description
The assay buffer (HFB) contained 20 mM HEPES (K) pH 7.3, 50 mM KCl, 5 mM MgCl2, 20 mM Na2MoO4, 0.01% NP40. Before each use, 0.1 mg/mL bovine gamma gl...

US Patent US10336757 (2019)


BindingDB Entry DOI: 10.7270/Q2VT1VF6
More data for this
Ligand-Target Pair