Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kallikrein-6 (Homo sapiens (Human)) | BDBM588055 (US11541023, Compound 3) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574434 (CHEMBL4861066) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Non-competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588057 (US11541023, Compound 5) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574435 (CHEMBL4862261) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574432 (CHEMBL4863108) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459512 (CHEMBL4211240) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of human KLK6 expressed in baculovirus/insect cell line system using Abz-KLRSSKQ-EDDnp substrate | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588058 (US11541023, Compound 6) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588056 (US11541023, Compound 4) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574431 (CHEMBL4847066) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588054 (US11541023, Compound 2) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | 2.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574433 (CHEMBL4852575) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574430 (CHEMBL4853943) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588053 (US11541023, Compound 1) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | 4.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50256261 (CHEMBL4059991) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bicycle Therapeutics Limited, Building 900, Babraham Research Campus , Cambridge CB22 3AT , U.K. Curated by ChEMBL | Assay Description Inhibition of recombinant human C-terminal His-tagged KLK6 isoform 1 (1 to 244 residues) expressed in HEK293 cells using fluorogenic Boc-QARAMC pepti... | J Med Chem 61: 2823-2836 (2018) Article DOI: 10.1021/acs.jmedchem.7b01625 BindingDB Entry DOI: 10.7270/Q2862JW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50256260 (CHEMBL4094403) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bicycle Therapeutics Limited, Building 900, Babraham Research Campus , Cambridge CB22 3AT , U.K. Curated by ChEMBL | Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasma | J Med Chem 61: 2823-2836 (2018) Article DOI: 10.1021/acs.jmedchem.7b01625 BindingDB Entry DOI: 10.7270/Q2862JW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50256262 (CHEMBL4070056) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bicycle Therapeutics Limited, Building 900, Babraham Research Campus , Cambridge CB22 3AT , U.K. Curated by ChEMBL | Assay Description Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma | J Med Chem 61: 2823-2836 (2018) Article DOI: 10.1021/acs.jmedchem.7b01625 BindingDB Entry DOI: 10.7270/Q2862JW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459537 (CHEMBL4217078) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459539 (CHEMBL4206734) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of KLK6 (unknown origin) expressed in Pichia pastoris pre-incubated for 10 mins before Boc-ValProArg-AMC substrate addition and measured a... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459525 (CHEMBL4212718) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459515 (CHEMBL4216138) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459538 (CHEMBL4218203) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459545 (CHEMBL4210314) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459527 (CHEMBL4203947) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459508 (CHEMBL4211164) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459535 (CHEMBL4214705) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459531 (CHEMBL4207925) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459522 (CHEMBL4218314) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459538 (CHEMBL4218203) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of KLK6 (unknown origin) expressed in Pichia pastoris pre-incubated for 10 mins before Boc-ValProArg-AMC substrate addition and measured a... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459516 (CHEMBL4211677) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459511 (CHEMBL4212332) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459529 (CHEMBL4208878) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588055 (US11541023, Compound 3) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459541 (CHEMBL4204137) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459526 (CHEMBL4218619) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588055 (US11541023, Compound 3) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR2) and 1 μl o... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459524 (CHEMBL4215806) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50386418 (CHEMBL2047313) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ... | ACS Med Chem Lett 3: 159-164 (2012) Article DOI: 10.1021/ml200291e BindingDB Entry DOI: 10.7270/Q2FN177M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588054 (US11541023, Compound 2) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588058 (US11541023, Compound 6) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574434 (CHEMBL4861066) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459520 (CHEMBL4203193) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574431 (CHEMBL4847066) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588055 (US11541023, Compound 3) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 2.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (MBP3) and 1 μl o... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588054 (US11541023, Compound 2) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 2.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR2) and 1 μl o... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459543 (CHEMBL4203033) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50386416 (CHEMBL2047314) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of N-terminus His6-tagged human kallikrein 6 expressed in baculovirus infected insect sf9 cells using Boc-Phe-Ser-Arg-AMC as substrate by ... | ACS Med Chem Lett 3: 159-164 (2012) Article DOI: 10.1021/ml200291e BindingDB Entry DOI: 10.7270/Q2FN177M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50574432 (CHEMBL4863108) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02175 BindingDB Entry DOI: 10.7270/Q2Z89H6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588057 (US11541023, Compound 5) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 3.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM50459507 (CHEMBL4215383) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
German Cancer Research Center (DKFZ) Curated by ChEMBL | Assay Description Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr... | J Med Chem 61: 8859-8874 (2018) Article DOI: 10.1021/acs.jmedchem.8b01106 BindingDB Entry DOI: 10.7270/Q279479B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-6 (Homo sapiens (Human)) | BDBM588056 (US11541023, Compound 4) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 5.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (PAR2) and 1 μl o... | Citation and Details BindingDB Entry DOI: 10.7270/Q2K35ZH4 | |||||||||||
More data for this Ligand-Target Pair |
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