Compile Data Set for Download or QSAR

Found 288 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2C'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015743 (Acetic acid 3-[1-(3,6-dihydro-2H-pyridin-1-yl)-cyc...) Show SMILES CC(=O)Oc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C19H25NO2/c1-16(21)22-18-10-8-9-17(15-18)19(11-4-2-5-12-19)20-13-6-3-7-14-20/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015738 (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-phe...) Show SMILES Oc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:18| Show InChI InChI=1S/C17H23NO/c19-16-9-7-8-15(14-16)17(10-3-1-4-11-17)18-12-5-2-6-13-18/h2,5,7-9,14,19H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015734 (1-(1-Thiophen-2-yl-cyclohexyl)-1,2,3,6-tetrahydro-...) Show SMILES C1CCC(CC1)(N1CCC=CC1)c1cccs1 |c:10| Show InChI InChI=1S/C15H21NS/c1-3-9-15(10-4-1,14-8-7-13-17-14)16-11-5-2-6-12-16/h2,5,7-8,13H,1,3-4,6,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015741 (1-[1-(3-Methoxy-phenyl)-cyclohexyl]-1,2,3,6-tetrah...) Show SMILES COc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C18H25NO/c1-20-17-10-8-9-16(15-17)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015732 (1-(1-Phenyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridin...) Show SMILES C1CCC(CC1)(N1CCC=CC1)c1ccccc1 |c:10| Show InChI InChI=1S/C17H23N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,3-5,8,10-11H,2,6-7,9,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015733 (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...) Show SMILES O=NCc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:20| Show InChI InChI=1S/C18H24N2O/c21-19-15-16-8-7-9-17(14-16)18(10-3-1-4-11-18)20-12-5-2-6-13-20/h2,5,7-9,14H,1,3-4,6,10-13,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015735 (1-(1-m-Tolyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridi...) Show SMILES Cc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:18| Show InChI InChI=1S/C18H25N/c1-16-9-8-10-17(15-16)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047				J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015744 (1-[1-(3-Methoxymethoxy-phenyl)-cyclohexyl]-1,2,3,6...) Show SMILES COCOc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C19H27NO2/c1-21-16-22-18-10-8-9-17(15-18)19(11-4-2-5-12-19)20-13-6-3-7-14-20/h3,6,8-10,15H,2,4-5,7,11-14,16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015740 (1-[1-(3-Vinyl-phenyl)-cyclohexyl]-1,2,3,6-tetrahyd...) Show SMILES C=Cc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C19H25N/c1-2-17-10-9-11-18(16-17)19(12-5-3-6-13-19)20-14-7-4-8-15-20/h2,4,7,9-11,16H,1,3,5-6,8,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018933 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) Show SMILES C[C@H]1CCC[C@@](C1)(N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H27N/c1-16-9-8-12-18(15-16,17-10-4-2-5-11-17)19-13-6-3-7-14-19/h2,4-5,10-11,16H,3,6-9,12-15H2,1H3/t16-,18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015731 (1-[1-(3-Methylsulfanyl-phenyl)-cyclohexyl]-1,2,3,6...) Show SMILES CSc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C18H25NS/c1-20-17-10-8-9-16(15-17)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h3,6,8-10,15H,2,4-5,7,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	231	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015736 (1-[1-(3-Fluoro-phenyl)-cyclohexyl]-1,2,3,6-tetrahy...) Show SMILES Fc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:18| Show InChI InChI=1S/C17H22FN/c18-16-9-7-8-15(14-16)17(10-3-1-4-11-17)19-12-5-2-6-13-19/h2,5,7-9,14H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	281	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015739 (3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...) Show SMILES O=Cc1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:19| Show InChI InChI=1S/C18H23NO/c20-15-16-8-7-9-17(14-16)18(10-3-1-4-11-18)19-12-5-2-6-13-19/h2,5,7-9,14-15H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50368882 (CHEMBL147585 | SK&F-10047 | SK-10047) Show SMILES CC1C2Cc3ccc(O)cc3C1CCN2CC=C |TLB:0:1:10.4.3:14.12.13,15:14:1:10.4.3,THB:9:10:1:14.12.13| Show InChI InChI=1S/C16H21NO/c1-3-7-17-8-6-14-11(2)16(17)9-12-4-5-13(18)10-15(12)14/h3-5,10-11,14,16,18H,1,6-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50368882 (CHEMBL147585 | SK&F-10047 | SK-10047) Show SMILES CC1C2Cc3ccc(O)cc3C1CCN2CC=C |TLB:0:1:10.4.3:14.12.13,15:14:1:10.4.3,THB:9:10:1:14.12.13| Show InChI InChI=1S/C16H21NO/c1-3-7-17-8-6-14-11(2)16(17)9-12-4-5-13(18)10-15(12)14/h3-5,10-11,14,16,18H,1,6-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested on Phencyclidine binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015730 (1-[1-(3-Trifluoromethyl-phenyl)-cyclohexyl]-1,2,3,...) Show SMILES FC(F)(F)c1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C18H22F3N/c19-18(20,21)16-9-7-8-15(14-16)17(10-3-1-4-11-17)22-12-5-2-6-13-22/h2,5,7-9,14H,1,3-4,6,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	422	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1ccccc1 Show InChI InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047				J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015742 (1-[1-(3-[1,3]Dioxolan-2-yl-phenyl)-cyclohexyl]-1,2...) Show SMILES C1COC(O1)c1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:23| Show InChI InChI=1S/C20H27NO2/c1-3-10-20(11-4-1,21-12-5-2-6-13-21)18-9-7-8-17(16-18)19-22-14-15-23-19/h2,5,7-9,16,19H,1,3-4,6,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	601	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50405724 (CHEMBL1169565) Show SMILES C1C2CC(CC12)[C@H](N1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C18H25N/c1-3-7-14(8-4-1)18(19-9-5-2-6-10-19)17-12-15-11-16(15)13-17/h1,3-4,7-8,15-18H,2,5-6,9-13H2/t15?,16?,17?,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCP				J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50038169 ((3R,4R)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...) Show SMILES C[C@@H]1CN(O)C(=O)[C@@H]1N Show InChI InChI=1S/C5H10N2O2/c1-3-2-7(9)5(8)4(3)6/h3-4,9H,2,6H2,1H3/t3-,4-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor				J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50405723 (CHEMBL1169564) Show SMILES C1C2CC(CC12)[C@@H](N1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C18H25N/c1-3-7-14(8-4-1)18(19-9-5-2-6-10-19)17-12-15-11-16(15)13-17/h1,3-4,7-8,15-18H,2,5-6,9-13H2/t15?,16?,17?,18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity of compound against Phencyclidine receptor by displacement of [3H]TCP				J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 |TLB:7:1:4.5.8:11,10:9:4:2.7.1,0:1:4:8.9.11,THB:7:5:11:2.1.12,12:1:4:8.9.11,12:9:4:2.7.1,6:5:11:2.1.12| Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound with the N-methyl-D-aspartate glutamate receptor blocking activity				J Med Chem 42: 1481-500 (1999) Article DOI: 10.1021/jm9805034 BindingDB Entry DOI: 10.7270/Q2HX1DCV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015745 (1-[1-(3-Benzyloxy-phenyl)-cyclohexyl]-1,2,3,6-tetr...) Show SMILES C(Oc1cccc(c1)C1(CCCCC1)N1CCC=CC1)c1ccccc1 |c:19| Show InChI InChI=1S/C24H29NO/c1-4-11-21(12-5-1)20-26-23-14-10-13-22(19-23)24(15-6-2-7-16-24)25-17-8-3-9-18-25/h1,3-5,8,10-14,19H,2,6-7,9,15-18,20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	733	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50038175 ((3R,4R)-3-Amino-1,4-dihydroxy-pyrrolidin-2-one | C...) Show SMILES N[C@@H]1[C@H](O)CN(O)C1=O Show InChI InChI=1S/C4H8N2O3/c5-3-2(7)1-6(9)4(3)8/h2-3,7,9H,1,5H2/t2-,3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor				J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM213888 (1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...) Show SMILES Sc1nnc2n1c1ccccc1[nH]c2=O Show InChI InChI=1S/C9H6N4OS/c14-8-7-11-12-9(15)13(7)6-4-2-1-3-5(6)10-8/h1-4H,(H,10,14)(H,12,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	>800	>-34.8	>3.00E+3	n/a	n/a	n/a	n/a	7.4	25
University of Copenhagen					Assay Description Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...				J Biol Chem 288: 33124-35 (2013) Article DOI: 10.1074/jbc.M113.480210 BindingDB Entry DOI: 10.7270/Q2MG7NB1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018932 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) Show SMILES C[C@@H]1CCC[C@@](C1)(N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H27N/c1-16-9-8-12-18(15-16,17-10-4-2-5-11-17)19-13-6-3-7-14-19/h2,4-5,10-11,16H,3,6-9,12-15H2,1H3/t16-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50288367 (3-(2,3-Dioxo-7-pyrrol-1-yl-6-trifluoromethyl-3,4-d...) Show SMILES OC(=O)CCn1c2cc(c(cc2[nH]c(=O)c1=O)C(F)(F)F)-n1cccc1 Show InChI InChI=1S/C16H12F3N3O4/c17-16(18,19)9-7-10-12(8-11(9)21-4-1-2-5-21)22(6-3-13(23)24)15(26)14(25)20-10/h1-2,4-5,7-8H,3,6H2,(H,20,25)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for binding affinity against glycine site of NMDA receptor using [3H]-glycine as a radioligand.				Bioorg Med Chem Lett 6: 2887-2892 (1996) Article DOI: 10.1016/S0960-894X(96)00534-3 BindingDB Entry DOI: 10.7270/Q23N23BK
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50048875 (CHEMBL431343 | N-[3-(5-Methoxy-1,2,3,4-tetrahydro-...) Show SMILES COc1cccc2C(CCCNCCNc3ccccc3)CCCc12 Show InChI InChI=1S/C22H30N2O/c1-25-22-14-6-12-20-18(8-5-13-21(20)22)9-7-15-23-16-17-24-19-10-3-2-4-11-19/h2-4,6,10-12,14,18,23-24H,5,7-9,13,15-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018929 (3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine | CHEM...) Show SMILES CC1CCCN(C1)C1(CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H27N/c1-16-9-8-14-19(15-16)18(12-6-3-7-13-18)17-10-4-2-5-11-17/h2,4-5,10-11,16H,3,6-9,12-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018929 (3-Methyl-1-(1-phenyl-cyclohexyl)-piperidine | CHEM...) Show SMILES CC1CCCN(C1)C1(CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H27N/c1-16-9-8-14-19(15-16)18(12-6-3-7-13-18)17-10-4-2-5-11-17/h2,4-5,10-11,16H,3,6-9,12-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Inhibition activity against binding of phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50038159 ((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...) Show SMILES N[C@@H]1CCN(O)C1=O Show InChI InChI=1S/C4H8N2O2/c5-3-1-2-6(8)4(3)7/h3,8H,1-2,5H2/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor				J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50405723 (CHEMBL1169564) Show SMILES C1C2CC(CC12)[C@@H](N1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C18H25N/c1-3-7-14(8-4-1)18(19-9-5-2-6-10-19)17-12-15-11-16(15)13-17/h1,3-4,7-8,15-18H,2,5-6,9-13H2/t15?,16?,17?,18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047				J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50405724 (CHEMBL1169565) Show SMILES C1C2CC(CC12)[C@H](N1CCCCC1)c1ccccc1 |r| Show InChI InChI=1S/C18H25N/c1-3-7-14(8-4-1)18(19-9-5-2-6-10-19)17-12-15-11-16(15)13-17/h1,3-4,7-8,15-18H,2,5-6,9-13H2/t15?,16?,17?,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity to sigma site of Phencyclidine receptor by displacement of [3H]-(+)-SKF- 10,047				J Med Chem 31: 1571-5 (1988) BindingDB Entry DOI: 10.7270/Q2WD41S2
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018931 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) Show SMILES C[C@H]1CCC[C@](C1)(N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H27N/c1-16-9-8-12-18(15-16,17-10-4-2-5-11-17)19-13-6-3-7-14-19/h2,4-5,10-11,16H,3,6-9,12-15H2,1H3/t16-,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50038157 (6-Hydroxy-2,6-diaza-bicyclo[3.2.1]octan-7-one | CH...) Show SMILES ON1C2CC(NCC2)C1=O |TLB:0:1:3:5.7.6,THB:9:8:3:5.7.6| Show InChI InChI=1S/C6H10N2O2/c9-6-5-3-4(8(6)10)1-2-7-5/h4-5,7,10H,1-3H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptor				J Med Chem 37: 4053-67 (1995) BindingDB Entry DOI: 10.7270/Q2JM28PT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50048867 (1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...) Show SMILES COc1cccc2C(CCCN3CCN(Cc4ccccc4)CC3)CCCc12 Show InChI InChI=1S/C25H34N2O/c1-28-25-14-6-12-23-22(10-5-13-24(23)25)11-7-15-26-16-18-27(19-17-26)20-21-8-3-2-4-9-21/h2-4,6,8-9,12,14,22H,5,7,10-11,13,15-20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50018930 (1-(3-Methyl-1-phenyl-cyclohexyl)-piperidine | CHEM...) Show SMILES C[C@@H]1CCC[C@](C1)(N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H27N/c1-16-9-8-12-18(15-16,17-10-4-2-5-11-17)19-13-6-3-7-14-19/h2,4-5,10-11,16H,3,6-9,12-15H2,1H3/t16-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.				J Med Chem 31: 1625-8 (1988) BindingDB Entry DOI: 10.7270/Q2M044DR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50007314 (CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) Show SMILES Clc1ccc(CCN[C@@H]2CCCC[C@@H]2N2CCCC2)cc1Cl Show InChI InChI=1S/C18H26Cl2N2/c19-15-8-7-14(13-16(15)20)9-10-21-17-5-1-2-6-18(17)22-11-3-4-12-22/h7-8,13,17-18,21H,1-6,9-12H2/t17-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Compound was tested for the inhibitory concentration against phencyclidine by using [3H]-TCP as radioligand at PCP receptor in guinea pig brain				J Med Chem 34: 3058-65 (1991) BindingDB Entry DOI: 10.7270/Q2VX0FGB
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50288358 ((2,3-Dioxo-7-pyrrol-1-yl-6-trifluoromethyl-3,4-dih...) Show SMILES OC(=O)Cn1c2cc(c(cc2[nH]c(=O)c1=O)C(F)(F)F)-n1cccc1 Show InChI InChI=1S/C15H10F3N3O4/c16-15(17,18)8-5-9-11(6-10(8)20-3-1-2-4-20)21(7-12(22)23)14(25)13(24)19-9/h1-6H,7H2,(H,19,24)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for binding affinity against glycine site of NMDA receptor using [3H]-glycine as a radioligand.				Bioorg Med Chem Lett 6: 2887-2892 (1996) Article DOI: 10.1016/S0960-894X(96)00534-3 BindingDB Entry DOI: 10.7270/Q23N23BK
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50048871 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) Show SMILES COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| Show InChI InChI=1S/C24H37N3O/c1-28-23-12-7-10-21-20(9-6-11-22(21)23)8-3-5-15-26-16-18-27(19-17-26)24-13-2-4-14-25-24/h7,10,12,20H,2-6,8-9,11,13-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50048873 (1-Benzyl-4-[3-(3,4-dihydro-naphthalen-1-yl)-propyl...) Show SMILES C(CN1CCN(Cc2ccccc2)CC1)CC1=CCCc2ccccc12 |t:18| Show InChI InChI=1S/C24H30N2/c1-2-8-21(9-3-1)20-26-18-16-25(17-19-26)15-7-13-23-12-6-11-22-10-4-5-14-24(22)23/h1-5,8-10,12,14H,6-7,11,13,15-20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 M				J Med Chem 39: 176-82 (1996) Article DOI: 10.1021/jm950409c BindingDB Entry DOI: 10.7270/Q2765G0J
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50015737 (1-[1-(3,5-Dimethoxy-phenyl)-cyclohexyl]-1,2,3,6-te...) Show SMILES COc1cc(OC)cc(c1)C1(CCCCC1)N1CCC=CC1 |c:21| Show InChI InChI=1S/C19H27NO2/c1-21-17-13-16(14-18(15-17)22-2)19(9-5-3-6-10-19)20-11-7-4-8-12-20/h4,7,13-15H,3,5-6,8-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.				J Med Chem 33: 2211-5 (1990) BindingDB Entry DOI: 10.7270/Q2BZ6515
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50037480 ((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...) Show SMILES CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21 |TLB:4:5:10:20.14.13,THB:19:20:10:5.7.6| Show InChI InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against PCP receptor from guinea pig brain, using [3H]TCP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50064173 (1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...) Show SMILES O=S1(=O)c2ccccc2CCC11CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23NO2S/c22-24(23)19-9-5-4-8-18(19)10-11-20(24)12-14-21(15-13-20)16-17-6-2-1-3-7-17/h1-9H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain				J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50064175 (1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...) Show SMILES O=S1c2ccccc2CCC11CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23NOS/c22-23-19-9-5-4-8-18(19)10-11-20(23)12-14-21(15-13-20)16-17-6-2-1-3-7-17/h1-9H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain				J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50064172 (1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...) Show SMILES C(N1CCC2(CC1)CCc1ccccc1S2)c1ccccc1 Show InChI InChI=1S/C20H23NS/c1-2-6-17(7-3-1)16-21-14-12-20(13-15-21)11-10-18-8-4-5-9-19(18)22-20/h1-9H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain				J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50036764 (1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-2,4'-...) Show SMILES O=C1c2ccccc2CCC11CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H23NO/c23-20-19-9-5-4-8-18(19)10-11-21(20)12-14-22(15-13-21)16-17-6-2-1-3-7-17/h1-9H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain				J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50064171 (1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...) Show SMILES C(N1CCC2(CC1)CCc1ccccc1O2)c1ccccc1 Show InChI InChI=1S/C20H23NO/c1-2-6-17(7-3-1)16-21-14-12-20(13-15-21)11-10-18-8-4-5-9-19(18)22-20/h1-9H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brain				J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q
					More data for this Ligand-Target Pair

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