Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thrombospondin-1 (Homo sapiens) | BDBM50541838![]() (CHEMBL4649483) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541831![]() (CHEMBL4644535) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541837![]() (CHEMBL4642848) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541836![]() (CHEMBL4642780) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541828![]() (CHEMBL4633877) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541833![]() (CHEMBL4636492) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541832![]() (CHEMBL4648099) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541830![]() (CHEMBL4647669) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541826![]() (CHEMBL4644244) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541839![]() (CHEMBL4649293) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541827![]() (CHEMBL4644046) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541834![]() (CHEMBL4644197) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541835![]() (CHEMBL4645518) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM50541829![]() (CHEMBL4638959) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA | ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521740![]() (US11149066, Compound 58) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.0910 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521739![]() (US11149066, Compound 24) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521738![]() (US11149066, Compound 13) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.0960 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521737![]() (US11149066, Compound 12) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521736![]() (US11149066, Compound 11) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521735![]() (US11149066, Compound 10) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.0910 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521734![]() (US11149066, Compound 9) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521733![]() (US11149066, Compound 7) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521732![]() (US11149066, Compound 6) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.440 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521731![]() (US11149066, Compound 5) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521730![]() (US11149066, Compound 4) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521729![]() (US11149066, Compound 3) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521728![]() (US11149066, Compound 2) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521741![]() (US11149066, Compound 75) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombospondin-1 (Homo sapiens) | BDBM521727![]() (US11149066, Compound 1) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B | |||||||||||
More data for this Ligand-Target Pair |