BindingDB PrimarySearch

Found 363 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Mus musculus (Mouse))	BDBM53441 (MLS001000876 \| N-(1H-benzimidazol-2-yl)-3-chlorany...) Show SMILES Clc1cccc(c1)C(=O)Nc1nc2ccccc2[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	400	-36.5	880	n/a	n/a	n/a	n/a	7.6	25
Brigham and Women's Hospital					Assay Description Inhibition activity and selectivity for UCH-L1 and UCH-L3.				Chem Biol 10: 837-46 (2003) Article DOI: 10.1016/j.chembiol.2003.08.010 BindingDB Entry DOI: 10.7270/Q20Z71P9
Brigham and Women's Hospital					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50514120 (CHEMBL3407553) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Competitive inhibition of UCHL1 in human H1299 cells using Ub-AMC substrate				J Med Chem 63: 2731-2750 (2020) Article DOI: 10.1021/acs.jmedchem.9b01138 BindingDB Entry DOI: 10.7270/Q2GF0XTC
Dana-Farber Cancer Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411563 (CHEMBL540117) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411574 (CHEMBL553923) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411577 (CHEMBL536998) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411568 (CHEMBL536764) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411581 (CHEMBL537224) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411570 (CHEMBL537225) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50326016 (3-amino-2-benzoyl-6-oxo-6,7-dihydrothieno[2,3-b]py...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL1				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50326016 (3-amino-2-benzoyl-6-oxo-6,7-dihydrothieno[2,3-b]py...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411572 (CHEMBL539345) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411573 (CHEMBL557989) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411575 (CHEMBL536763) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411579 (CHEMBL539346) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411566 (CHEMBL536995) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411567 (CHEMBL537227) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411578 (CHEMBL539094) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411580 (CHEMBL557988) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411562 (CHEMBL540118) Show SMILES CC(=O)c1sc2[nH]c(=O)c(cc2c1N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411571 (CHEMBL537226) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411576 (CHEMBL556784) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411569 (CHEMBL538583) Show SMILES NC(=O)c1sc2[nH]c(=O)c(cc2c1N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50411564 (CHEMBL536997) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of UCHL1				Bioorg Med Chem Lett 17: 3729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.04.027 BindingDB Entry DOI: 10.7270/Q2HT2QJ5
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445149 ((2S,4S)-4-Fluoro-2-(4-(5-methyl-1H-pyrazol-4-yl)in...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM552974 ((2S,4S)-4-fluoro-2-(4-(5- \| US11319287, Example 29) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445160 ((S)-2-(4-(1H-pyrrolo[2,3-b]- pyridin-4-yl)indoline...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445158 ((S)-2-(5-(3-(trifluoro- methyl)-1H-pyrazol-4- yl)i...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445088 ((S)-2-(4-(1H-pyrrolo [2,3-b]pyridin-3- yl)indoline...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445080 ((S)-2-(4-(5-(Trifluoromethyl)-1H-pyrazol-4-yl)indo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445149 ((2S,4S)-4-Fluoro-2-(4-(5-methyl-1H-pyrazol-4-yl)in...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
MISSION THERAPEUTICS LIMITED US Patent					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445080 ((S)-2-(4-(5-(Trifluoromethyl)-1H-pyrazol-4-yl)indo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
MISSION THERAPEUTICS LIMITED US Patent					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445088 ((S)-2-(4-(1H-pyrrolo [2,3-b]pyridin-3- yl)indoline...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
MISSION THERAPEUTICS LIMITED US Patent					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445090 ((2S,4S)-4-fluoro-2-(4-(5-(trifluoromethyl)-1H-pyra...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
MISSION THERAPEUTICS LIMITED US Patent					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445158 ((S)-2-(5-(3-(trifluoro- methyl)-1H-pyrazol-4- yl)i...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
MISSION THERAPEUTICS LIMITED US Patent					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445160 ((S)-2-(4-(1H-pyrrolo[2,3-b]- pyridin-4-yl)indoline...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
MISSION THERAPEUTICS LIMITED US Patent					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50594734 (CHEMBL5191704) Show SMILES O=C(Nc1ncc(s1)N1CCOCC1)C1CCN(C1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50589875 (8RK64) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01113 BindingDB Entry DOI: 10.7270/Q21C21TN
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50589875 (8RK64) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01113 BindingDB Entry DOI: 10.7270/Q21C21TN
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445098 ((S)-2-(4-(3-cyclopropyl-1H- pyrazol-4-yl)indoline-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445099 ((S)-2-(4-(2-aminopyrimidin- 4-yl)indoline-1- carbo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445100 ((S)-2-(4-(Pyridin-4-yl)indoline-1-carbonyl)pyrroli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445107 ((S)-1-Cyano-N-(4-(2-methoxyphenyl)thiazol-2-yl)-N-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445108 ((S)-1-cyano-N-(4-(3- methoxyphenyl)thiazol-2- yl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445113 ((S)-N-(4-(3-chlorophenyl)- thiazol-2-yl)-1-cyano-N...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445114 ((S)-N-(4-(2-chlorophenyl)- thiazol-2-yl)-1-cyano-N...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445115 ((S)-1-cyano-N-methyl-N-(4-phenylthiazol-2-yl)pyrro...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445132 ((2S,4S)-1-Cyano-4-methoxy-N-methyl-N-(4-phenylthia...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445135 (4-(1-(Cyano-L-prolyl)indolin-4-yl)-1H-pyrazole-5-c...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445137 ((S)-2-(4-(2-Aminopyridin-4-yl)indoline-1-carbonyl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445140 ((S)-1-cyano-N-(4- (6-methoxypyridin- 2-yl)thiazol-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
TBA					More data for this Ligand-Target Pair

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