Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L1' and Ligand = 'BDBM445107'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445107 ((S)-1-Cyano-N-(4-(2-methoxyphenyl)thiazol-2-yl)-N-...) Show SMILES COc1ccccc1-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N |r| Show InChI InChI=1S/C17H18N4O2S/c1-20(16(22)14-7-5-9-21(14)11-18)17-19-13(10-24-17)12-6-3-4-8-15(12)23-2/h3-4,6,8,10,14H,5,7,9H2,1-2H3/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CN774X
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM445107 ((S)-1-Cyano-N-(4-(2-methoxyphenyl)thiazol-2-yl)-N-...) Show SMILES COc1ccccc1-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N |r| Show InChI InChI=1S/C17H18N4O2S/c1-20(16(22)14-7-5-9-21(14)11-18)17-19-13(10-24-17)12-6-3-4-8-15(12)23-2/h3-4,6,8,10,14H,5,7,9H2,1-2H3/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...				US Patent US10669234 (2020) BindingDB Entry DOI: 10.7270/Q22N559S
					More data for this Ligand-Target Pair