Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with Target = 'Glycoprotein G'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombospondin-1 (Homo sapiens)	BDBM50541838 (CHEMBL4649483) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C17H33N5O5/c1-10(2)8-13(15(19)25)22-16(26)12(6-4-5-7-18)21-17(27)14(9-23)20-11(3)24/h10,12-14,23H,4-9,18H2,1-3H3,(H2,19,25)(H,20,24)(H,21,27)(H,22,26)/t12-,13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541831 (CHEMBL4644535) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN(C)C)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C19H37N5O5/c1-12(2)10-15(17(20)27)23-18(28)14(8-6-7-9-24(4)5)22-19(29)16(11-25)21-13(3)26/h12,14-16,25H,6-11H2,1-5H3,(H2,20,27)(H,21,26)(H,22,29)(H,23,28)/t14-,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541837 (CHEMBL4642848) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C17H33N5O5/c1-10(2)8-13(15(19)25)22-16(26)12(6-4-5-7-18)21-17(27)14(9-23)20-11(3)24/h10,12-14,23H,4-9,18H2,1-3H3,(H2,19,25)(H,20,24)(H,21,27)(H,22,26)/t12-,13+,14+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541836 (CHEMBL4642780) Show SMILES CC(C)C[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C17H33N5O5/c1-10(2)8-13(15(19)25)22-16(26)12(6-4-5-7-18)21-17(27)14(9-23)20-11(3)24/h10,12-14,23H,4-9,18H2,1-3H3,(H2,19,25)(H,20,24)(H,21,27)(H,22,26)/t12-,13+,14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541828 (CHEMBL4633877) Show SMILES CC(C)C[C@H](N(C)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C18H35N5O5/c1-11(2)9-15(16(20)26)23(4)18(28)13(7-5-6-8-19)22-17(27)14(10-24)21-12(3)25/h11,13-15,24H,5-10,19H2,1-4H3,(H2,20,26)(H,21,25)(H,22,27)/t13-,14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541833 (CHEMBL4636492) Show SMILES CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O |r| Show InChI InChI=1S/C19H37N5O5/c1-11(2)10-15(17(27)21-5)24-18(28)14(8-6-7-9-20)23-19(29)16(12(3)25)22-13(4)26/h11-12,14-16,25H,6-10,20H2,1-5H3,(H,21,27)(H,22,26)(H,23,29)(H,24,28)/t12-,14-,15+,16+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541832 (CHEMBL4648099) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(C)=O)C(=O)N(C)C |r| Show InChI InChI=1S/C19H37N5O5/c1-12(2)10-15(19(29)24(4)5)23-17(27)14(8-6-7-9-20)22-18(28)16(11-25)21-13(3)26/h12,14-16,25H,6-11,20H2,1-5H3,(H,21,26)(H,22,28)(H,23,27)/t14-,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541830 (CHEMBL4647669) Show SMILES CNCCCC[C@H](NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(N)=O |r| Show InChI InChI=1S/C18H35N5O5/c1-11(2)9-14(16(19)26)23-17(27)13(7-5-6-8-20-4)22-18(28)15(10-24)21-12(3)25/h11,13-15,20,24H,5-10H2,1-4H3,(H2,19,26)(H,21,25)(H,22,28)(H,23,27)/t13-,14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541826 (CHEMBL4644244) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C17H33N5O5/c1-10(2)8-13(15(19)25)22-16(26)12(6-4-5-7-18)21-17(27)14(9-23)20-11(3)24/h10,12-14,23H,4-9,18H2,1-3H3,(H2,19,25)(H,20,24)(H,21,27)(H,22,26)/t12-,13-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541839 (CHEMBL4649293) Show SMILES CC(=O)N[C@@H](CCCN)C(=O)NC(C)(C)C(N)=O |r| Show InChI InChI=1S/C11H22N4O3/c1-7(16)14-8(5-4-6-12)9(17)15-11(2,3)10(13)18/h8H,4-6,12H2,1-3H3,(H2,13,18)(H,14,16)(H,15,17)/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541827 (CHEMBL4644046) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C18H34N6O5/c1-10(2)8-13(16(21)27)24-17(28)12(6-4-5-7-19)23-18(29)14(9-15(20)26)22-11(3)25/h10,12-14H,4-9,19H2,1-3H3,(H2,20,26)(H2,21,27)(H,22,25)(H,23,29)(H,24,28)/t12-,13-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541834 (CHEMBL4644197) Show SMILES CCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O |r| Show InChI InChI=1S/C18H35N5O5/c1-4-15(25)21-14(10-24)18(28)22-12(7-5-6-8-19)17(27)23-13(16(20)26)9-11(2)3/h11-14,24H,4-10,19H2,1-3H3,(H2,20,26)(H,21,25)(H,22,28)(H,23,27)/t12-,13-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541835 (CHEMBL4645518) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(C)=O)C(N)=O |r| Show InChI InChI=1S/C16H31N5O4/c1-10(2)8-13(15(18)24)21-16(25)12(6-4-5-7-17)20-14(23)9-19-11(3)22/h10,12-13H,4-9,17H2,1-3H3,(H2,18,24)(H,19,22)(H,20,23)(H,21,25)/t12-,13-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM50541829 (CHEMBL4638959) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CO)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C19H35N5O6/c1-11(2)9-15(17(20)28)24-18(29)14(7-5-6-8-21-12(3)26)23-19(30)16(10-25)22-13(4)27/h11,14-16,25H,5-10H2,1-4H3,(H2,20,28)(H,21,26)(H,22,27)(H,23,30)(H,24,29)/t14-,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of TSP1 in human myeloma cells assessed reduction in TGFbeta activity incubated for 1 hr by ELISA				ACS Med Chem Lett 11: 1130-1136 (2020) Article DOI: 10.1021/acsmedchemlett.9b00540 BindingDB Entry DOI: 10.7270/Q2M330BV
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521734 (US11149066, Compound 9) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521735 (US11149066, Compound 10) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0910	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521736 (US11149066, Compound 11) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521737 (US11149066, Compound 12) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC1=O)[C@@H](C)O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521738 (US11149066, Compound 13) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC1=O)[C@@H](C)O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0960	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521739 (US11149066, Compound 24) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521740 (US11149066, Compound 58) Show SMILES CCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(C)C)C(N)=O)[C@@H](C)CC |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.0910	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521733 (US11149066, Compound 7) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521732 (US11149066, Compound 6) Show SMILES CC(C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC1=O)C(N)=O)C(C)C |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521731 (US11149066, Compound 5) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521730 (US11149066, Compound 4) Show SMILES CC[C@H](C)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](CO)NC1=O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521729 (US11149066, Compound 3) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521728 (US11149066, Compound 2) Show SMILES CC(C)[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)CSC[C@H](NC1=O)C(N)=O)C(C)C)C(C)C |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521727 (US11149066, Compound 1) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC1=O)C(C)C)C(C)C)C(C)C)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Glycoprotein G (Nipah virus)	BDBM50293787 ((2R,6S)-1-allyl-4-hydroxy-2,6-bis(4-nitrophenyl)-1...) Show SMILES CCOC(=O)C1[C@@H](N(CC=C)[C@H](C(C(=O)OCC)C1=O)c1ccc(cc1)[N+]([O-])=O)c1ccc(cc1)[N+]([O-])=O |r| Show InChI InChI=1S/C26H27N3O9/c1-4-15-27-22(16-7-11-18(12-8-16)28(33)34)20(25(31)37-5-2)24(30)21(26(32)38-6-3)23(27)17-9-13-19(14-10-17)29(35)36/h4,7-14,20-23H,1,5-6,15H2,2-3H3/t20?,21?,22-,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
					More data for this Ligand-Target Pair
Glycoprotein G (Nipah virus)	BDBM50293786 (CHEMBL551897 | Ethyl 4-[1-cyclopropyl-3-(2,4-dichl...) Show SMILES CCOC(=O)N1CCN(CC1)c1cc2n(cc(C(=O)NCc3ccc(Cl)cc3Cl)c(=O)c2cc1F)C1CC1 Show InChI InChI=1S/C27H27Cl2FN4O4/c1-2-38-27(37)33-9-7-32(8-10-33)24-13-23-19(12-22(24)30)25(35)20(15-34(23)18-5-6-18)26(36)31-14-16-3-4-17(28)11-21(16)29/h3-4,11-13,15,18H,2,5-10,14H2,1H3,(H,31,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
					More data for this Ligand-Target Pair
Glycoprotein G (Nipah virus)	BDBM50293785 (CHEMBL562236 | Ethyl 4-[3-(2,4-dichlorobenzylcarba...) Show SMILES CCOC(=O)N1CCN(CC1)c1cc2n(CC)cc(C(=O)NCc3ccc(Cl)cc3Cl)c(=O)c2cc1F Show InChI InChI=1S/C26H27Cl2FN4O4/c1-3-31-15-19(25(35)30-14-16-5-6-17(27)11-20(16)28)24(34)18-12-21(29)23(13-22(18)31)32-7-9-33(10-8-32)26(36)37-4-2/h5-6,11-13,15H,3-4,7-10,14H2,1-2H3,(H,30,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
					More data for this Ligand-Target Pair
Glycoprotein G (Nipah virus)	BDBM50293784 (CHEMBL559961 | Ethyl 1-[3-(2,4-dichlorobenzylcarba...) Show SMILES CCOC(=O)C1CCN(CC1)c1cc2n(CC)cc(C(=O)NCc3ccc(Cl)cc3Cl)c(=O)c2cc1F Show InChI InChI=1S/C27H28Cl2FN3O4/c1-3-32-15-20(26(35)31-14-17-5-6-18(28)11-21(17)29)25(34)19-12-22(30)24(13-23(19)32)33-9-7-16(8-10-33)27(36)37-4-2/h5-6,11-13,15-16H,3-4,7-10,14H2,1-2H3,(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
					More data for this Ligand-Target Pair
Glycoprotein G (Nipah virus)	BDBM50293783 (7-(4-Carbamoylpiperidin-1-yl)-1-cyclopropyl-N-(2,4...) Show SMILES NC(=O)C1CCN(CC1)c1cc2n(cc(C(=O)NCc3ccc(Cl)cc3Cl)c(=O)c2cc1F)C1CC1 Show InChI InChI=1S/C26H25Cl2FN4O3/c27-16-2-1-15(20(28)9-16)12-31-26(36)19-13-33(17-3-4-17)22-11-23(21(29)10-18(22)24(19)34)32-7-5-14(6-8-32)25(30)35/h1-2,9-11,13-14,17H,3-8,12H2,(H2,30,35)(H,31,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
					More data for this Ligand-Target Pair
Thrombospondin-1 (Homo sapiens)	BDBM521741 (US11149066, Compound 75) Show SMILES CCCC[C@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)CNC(=O)CSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC1=O)C(C)C)C(N)=O)[C@@H](C)CC |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WH2T4B
					More data for this Ligand-Target Pair
Glycoprotein G (Nipah virus)	BDBM50193260 (2-benzylbenzo[d]oxazol-5-amine | CHEMBL214087) Show SMILES Nc1ccc2oc(Cc3ccccc3)nc2c1 Show InChI InChI=1S/C14H12N2O/c15-11-6-7-13-12(9-11)16-14(17-13)8-10-4-2-1-3-5-10/h1-7,9H,8,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
					More data for this Ligand-Target Pair
Glycoprotein G (Nipah virus)	BDBM50293782 (CHEMBL551697 | N-(4-Chlorobenzyl)-1-ethyl-4-oxo-7-...) Show SMILES CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2ccc(cc12)C(F)(F)F Show InChI InChI=1S/C20H16ClF3N2O2/c1-2-26-11-16(19(28)25-10-12-3-6-14(21)7-4-12)18(27)15-8-5-13(9-17(15)26)20(22,23)24/h3-9,11H,2,10H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a
University of W£rzburg Curated by ChEMBL					Assay Description Inhibition of Nipah virus glycoprotein G/F-mediated cell-cell fusion expressed in african green monkey Vero cells after 24 hrs relative to untreated ...				J Med Chem 52: 4257-65 (2009) Article DOI: 10.1021/jm900411s BindingDB Entry DOI: 10.7270/Q2H1322G
					More data for this Ligand-Target Pair