Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50388546 (CHEMBL213072 | CHEMBL333363) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant Tdp1 after 1 hr by FRET assay | J Med Chem 55: 4457-78 (2012) Article DOI: 10.1021/jm300335n BindingDB Entry DOI: 10.7270/Q2SB46TZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50534270 (CHEMBL4464463) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 15 mins by PAGE analysis | Bioorg Med Chem 24: 5017-5027 (2016) Article DOI: 10.1016/j.bmc.2016.09.045 BindingDB Entry DOI: 10.7270/Q27D2ZNS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546508 (CHEMBL4746230) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM60996 (5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 20 mins by PAGE analysis | Bioorg Med Chem 24: 5017-5027 (2016) Article DOI: 10.1016/j.bmc.2016.09.045 BindingDB Entry DOI: 10.7270/Q27D2ZNS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546509 (CHEMBL4760174) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50589478 (CHEMBL5187480) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128909 BindingDB Entry DOI: 10.7270/Q2833WZK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM60996 (5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli Rosetta2(DE3) using 3'-FITC labeled 13-mer DNA as substrate by Gyrasol ... | Bioorg Med Chem 24: 5017-5027 (2016) Article DOI: 10.1016/j.bmc.2016.09.045 BindingDB Entry DOI: 10.7270/Q27D2ZNS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50534268 (CHEMBL4571632) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-32P-labeled N14Y DNA substrate incubated for 15 mins by PAGE analysis | Bioorg Med Chem 24: 5017-5027 (2016) Article DOI: 10.1016/j.bmc.2016.09.045 BindingDB Entry DOI: 10.7270/Q27D2ZNS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463376 (CHEMBL4244758) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507151 (CHEMBL4438274) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507151 (CHEMBL4438274) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128909 BindingDB Entry DOI: 10.7270/Q2833WZK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546512 (CHEMBL4799682) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546515 (CHEMBL4756604) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507140 (CHEMBL4440514) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546513 (CHEMBL4761724) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546514 (CHEMBL4750455) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463381 (CHEMBL4241424) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463368 (CHEMBL4250901) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507150 (CHEMBL4440114) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463384 (CHEMBL4242066) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507155 (CHEMBL4587610) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546511 (CHEMBL4745693) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530468 (CHEMBL4436247) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530468 (CHEMBL4436247) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50540219 (CHEMBL4642359) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115234 BindingDB Entry DOI: 10.7270/Q2T72N03 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530462 (CHEMBL4435210) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530462 (CHEMBL4435210) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM11995 (2-chloro-5-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic ac...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of Tdp1 (unknown origin) | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530469 (CHEMBL4442276) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530469 (CHEMBL4442276) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50546510 (CHEMBL4797909) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 139 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli using 5'-FAM/3'-BHQ1 tagged oligonucleotide as substrate by fluorescenc... | Citation and Details Article DOI: 10.1021/acs.jnatprod.9b01089 BindingDB Entry DOI: 10.7270/Q29S1VNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463372 (CHEMBL3356739) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507156 (CHEMBL4475772) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507139 (CHEMBL4446104) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463379 (CHEMBL4243917) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50232848 (CHEMBL4084310) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet... | J Nat Prod 79: 2961-2967 (2016) BindingDB Entry DOI: 10.7270/Q20C4Z0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507153 (CHEMBL4551119) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50232847 (CHEMBL4090202) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet... | J Nat Prod 79: 2961-2967 (2016) BindingDB Entry DOI: 10.7270/Q20C4Z0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530467 (CHEMBL4467521) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530467 (CHEMBL4467521) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50507152 (CHEMBL4436400) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc... | Eur J Med Chem 161: 581-593 (2019) Article DOI: 10.1016/j.ejmech.2018.10.055 BindingDB Entry DOI: 10.7270/Q2B56P1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50067508 (CHEMBL3401896) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) assessed as increase in fluorescence | Bioorg Med Chem 23: 2044-52 (2015) Article DOI: 10.1016/j.bmc.2015.03.020 BindingDB Entry DOI: 10.7270/Q2ZW1NMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463373 (CHEMBL4250945) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463364 (CHEMBL4249351) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 232 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50232843 (CHEMBL2207624) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet... | J Nat Prod 79: 2961-2967 (2016) BindingDB Entry DOI: 10.7270/Q20C4Z0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50540222 (CHEMBL4643271) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115234 BindingDB Entry DOI: 10.7270/Q2T72N03 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50540220 (CHEMBL4643649) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of TDP1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C- BHQ1)-3' as substrate measured for every 1 min by fluorescence based ass... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115234 BindingDB Entry DOI: 10.7270/Q2T72N03 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530466 (CHEMBL4447343) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50530466 (CHEMBL4447343) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | J Nat Prod 82: 2443-2450 (2019) Article DOI: 10.1021/acs.jnatprod.8b01095 BindingDB Entry DOI: 10.7270/Q23T9MPN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens (Human)) | BDBM50463386 (CHEMBL4242317) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Siberian Branch of the Russian Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl... | Bioorg Med Chem 26: 4470-4480 (2018) Article DOI: 10.1016/j.bmc.2018.07.039 BindingDB Entry DOI: 10.7270/Q27W6FVM | |||||||||||
More data for this Ligand-Target Pair |
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