Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxyanthranilate 3,4-dioxygenase (Homo sapiens (Human)) | BDBM50446510 (CHEMBL3110069) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of 3-HAO in human brain homogenates using [1-14C]-3-HANA as substrate assessed as [14C]-QUIN production after 1 hr by liquid scintillation... | J Med Chem 56: 9482-95 (2014) Article DOI: 10.1021/jm401249c BindingDB Entry DOI: 10.7270/Q21N82MD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxyanthranilate 3,4-dioxygenase (Rattus norvegicus) | BDBM50446510 (CHEMBL3110069) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of 3-HAO in Sprague-Dawley rat brain homogenates using [1-14C]-3-HANA as substrate assessed as [14C]-QUIN production after 1 hr by liquid ... | J Med Chem 56: 9482-95 (2014) Article DOI: 10.1021/jm401249c BindingDB Entry DOI: 10.7270/Q21N82MD | |||||||||||
More data for this Ligand-Target Pair |