BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Type IV secretion-like conjugative transfer relaxase protein TraI'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Type IV secretion-like conjugative transfer relaxase protein TraI (Escherichia coli (strain SMS-3-5 / SECEC))	BDBM50478336 (Imidobisphosphate \| Imidodiphosphate) Show SMILES OP(O)(=O)NP(O)(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assay				Proc Natl Acad Sci U S A 104: 12282-7 (2007) Article DOI: 10.1073/pnas.0702760104 BindingDB Entry DOI: 10.7270/Q2PK0JXD
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Type IV secretion-like conjugative transfer relaxase protein TraI (Escherichia coli (strain SMS-3-5 / SECEC))	BDBM50478336 (Imidobisphosphate \| Imidodiphosphate) Show SMILES OP(O)(=O)NP(O)(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by uncompetitive inhibition assay				Proc Natl Acad Sci U S A 104: 12282-7 (2007) Article DOI: 10.1073/pnas.0702760104 BindingDB Entry DOI: 10.7270/Q2PK0JXD
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Type IV secretion-like conjugative transfer relaxase protein TraI (Escherichia coli (strain SMS-3-5 / SECEC))	BDBM50216172 ((Dichloro-phosphono-methyl)-phosphonic acid \| CHEM...) Show SMILES OP(O)(=O)C(Cl)(Cl)P(O)(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assay				Proc Natl Acad Sci U S A 104: 12282-7 (2007) Article DOI: 10.1073/pnas.0702760104 BindingDB Entry DOI: 10.7270/Q2PK0JXD
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Type IV secretion-like conjugative transfer relaxase protein TraI (Escherichia coli (strain SMS-3-5 / SECEC))	BDBM50115102 ((1-Hydroxy-1-phosphono-ethyl)-phosphonic acid \| CH...) Show SMILES CC(O)(P(O)(O)=O)P(O)(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assay				Proc Natl Acad Sci U S A 104: 12282-7 (2007) Article DOI: 10.1073/pnas.0702760104 BindingDB Entry DOI: 10.7270/Q2PK0JXD
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair
Type IV secretion-like conjugative transfer relaxase protein TraI (Escherichia coli (strain SMS-3-5 / SECEC))	BDBM50162816 (CHEMBL180570 \| Medronic acid \| Methylene diphsphon...) Show SMILES OP(O)(=O)CP(O)(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina Curated by ChEMBL					Assay Description Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assay				Proc Natl Acad Sci U S A 104: 12282-7 (2007) Article DOI: 10.1073/pnas.0702760104 BindingDB Entry DOI: 10.7270/Q2PK0JXD
University of North Carolina Curated by ChEMBL					More data for this Ligand-Target Pair