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Found 92 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571527
PNG
((rac)-(rac-15)-benzyl-4-chloro-3-ethyl-7-{3-[(6-fl...)
Show SMILES CCc1c-2c(nn1C)C(Cc1ccccc1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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n/an/a 1.22E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571495
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13)c1ccccc1
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n/an/a 1.32E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571496
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)C(CCC1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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n/an/a 1.41E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571472
PNG
((−)-4-chloro-15-cyclopropyl-2,3-dimethyl-7-{...)
Show SMILES Cc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13)C1CC1
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n/an/a 1.46E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571475
PNG
((+)-4-chloro-15-cyclopropyl-3-ethyl-7-{3-[(6-fluor...)
Show SMILES CCc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13)C1CC1
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n/an/a 1.51E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571488
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)C(CC(C)(C)O)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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n/an/a 1.59E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571474
PNG
((rac)-4-chloro-(15-rac)-cyclopropyl-3-ethyl-7-{3-[...)
Show SMILES CCc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13)C1CC1
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n/an/a 1.63E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571469
PNG
((+)-4-chloro-3-ethyl-2-methyl-7-{3-[(naphthalen-1-...)
Show SMILES CCc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13)C(F)(F)F
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n/an/a 1.63E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM572222
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)N(C)CCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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n/an/a 1.70E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2057K58
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571489
PNG
((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...)
Show SMILES CCc1c-2c(nn1C)C(CC(C)(C)O)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571470
PNG
((−)-4-chloro-3-ethyl-2-methyl-7-{3-[(naphtha...)
Show SMILES CCc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13)C(F)(F)F
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n/an/a 1.78E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571477
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)C(CCOC)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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n/an/a 1.81E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571476
PNG
((−)-4-chloro-15-cyclopropyl-3-ethyl-7-{3-[(6...)
Show SMILES CCc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13)C1CC1
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n/an/a 1.83E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571463
PNG
((rac)-4-Chloro-3-ethyl-2-methyl-7-{3-[(naphthalen-...)
Show SMILES CCc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13)C(F)(F)F
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n/an/a 1.86E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM572202
PNG
((rac)-4-chloro-12,12-difluoro-2,3-dimethyl-7-{3-[(...)
Show SMILES CCc1c-2c(COCC(F)(F)CCn3c(C(O)=O)c(CCCOc4cccc5cc(F)ccc45)c4ccc(Cl)c-2c34)nn1C
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n/an/a 1.88E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2057K58
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM572219
PNG
((rac)-4-chloro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES CN1CCCCCn2c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c(-c4c(C)n(C)nc14)c23
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n/an/a 1.90E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2057K58
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM572219
PNG
((rac)-4-chloro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES CN1CCCCCn2c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c(-c4c(C)n(C)nc14)c23
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TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2057K58
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571479
PNG
((−)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthal...)
Show SMILES CCc1c-2c(nn1C)C(CCOC)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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n/an/a 1.93E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571510
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)C(CCC(C)(C)O)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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n/an/a 1.96E+4n/an/an/an/an/an/a


TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571437
PNG
((rac)-2,3,15-trimethyl-7-[3-(naphthalen-1-yloxy)pr...)
Show SMILES CC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3cccc(-c4c(C)n(C)nc14)c23
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TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571437
PNG
((rac)-2,3,15-trimethyl-7-[3-(naphthalen-1-yloxy)pr...)
Show SMILES CC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3cccc(-c4c(C)n(C)nc14)c23
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Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571437
PNG
((rac)-2,3,15-trimethyl-7-[3-(naphthalen-1-yloxy)pr...)
Show SMILES CC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3cccc(-c4c(C)n(C)nc14)c23
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Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571440
PNG
((rac)-2,3-dimethyl-15-[2-(morpholin-4-yl)ethyl]-7-...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3cccc-2c13
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Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571443
PNG
((rac)-4-fluoro-2,3-dimethyl-15-[2-(morpholin-4-yl)...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(F)c-2c13
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TBA

Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571443
PNG
((rac)-4-fluoro-2,3-dimethyl-15-[2-(morpholin-4-yl)...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(F)c-2c13
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Assay Description
The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571446
PNG
((rac)-3-ethyl-4-fluoro-2-methyl-15-[2-(morpholin-4...)
Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(F)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571446
PNG
((rac)-3-ethyl-4-fluoro-2-methyl-15-[2-(morpholin-4...)
Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(F)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


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BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571449
PNG
((rac)-4-chloro-2,3-dimethyl-15-[2-(morpholin-4-yl)...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13
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Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571449
PNG
((rac)-4-chloro-2,3-dimethyl-15-[2-(morpholin-4-yl)...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13
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Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571449
PNG
((rac)-4-chloro-2,3-dimethyl-15-[2-(morpholin-4-yl)...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13
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BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571452
PNG
((rac)-4-chloro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


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BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571452
PNG
((rac)-4-chloro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


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BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571452
PNG
((rac)-4-chloro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571455
PNG
((rac)-4-fluoro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(F)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571455
PNG
((rac)-4-fluoro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(F)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571455
PNG
((rac)-4-fluoro-7-{3-[(6-fluoronaphthalen-1-yl)oxy]...)
Show SMILES Cc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(F)c-2c13
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BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571458
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571459
PNG
((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...)
Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571460
PNG
((−)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthal...)
Show SMILES CCc1c-2c(nn1C)C(CCN1CCOCC1)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571461
PNG
((rac)-4-chloro-15-ethyl-2,3-dimethyl-7-{3-[(naphth...)
Show SMILES CCC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c(-c4c(C)n(C)nc14)c23
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571462
PNG
((rac)-4-chloro-15-(2-hydroxyethyl)-2,3-dimethyl-7-...)
Show SMILES Cc1c-2c(nn1C)C(CCO)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571464
PNG
((rac)-4-Chloro-15-cyclopropyl-2,3-dimethyl-7-{3-[(...)
Show SMILES Cc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13)C1CC1
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571465
PNG
((+)-4-chloro-15-ethyl-2,3-dimethyl-7-{3-[(naphthal...)
Show SMILES CCC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c(-c4c(C)n(C)nc14)c23
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571466
PNG
((−)-4-chloro-15-ethyl-2,3-dimethyl-7-{3-[(na...)
Show SMILES CCC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c(-c4c(C)n(C)nc14)c23
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571467
PNG
((+)-4-chloro-15-(2-hydroxyethyl)-2,3-dimethyl-7-{3...)
Show SMILES Cc1c-2c(nn1C)C(CCO)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571468
PNG
((−)-4-chloro-15-(2-hydroxyethyl)-2,3-dimethy...)
Show SMILES Cc1c-2c(nn1C)C(CCO)OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571471
PNG
((+)-4-chloro-15-cyclopropyl-2,3-dimethyl-7-{3-[(na...)
Show SMILES Cc1c-2c(nn1C)C(OCCCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c-2c13)C1CC1
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571473
PNG
((rac)-4-chloro-(15-rac)-(2-methoxyethyl)-2,3-dimet...)
Show SMILES COCCC1OCCCCn2c(C(O)=O)c(CCCOc3cccc4ccccc34)c3ccc(Cl)c(-c4c(C)n(C)nc14)c23
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571478
PNG
((+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-y...)
Show SMILES CCc1c-2c(nn1C)C(CCOC)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2 [1-211]/Bad BH3 Peptide


(Homo sapiens (Human))
BDBM571480
PNG
((rac)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1...)
Show SMILES CCc1c-2c(nn1C)C(CCO)OCCCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
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The dose-dependent inhibition by the compounds described in this invention of the interaction between BCL-2 and the BH3 domain of Bad (both human) wa...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2J38WT5
More data for this
Ligand-Target Pair
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