Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240885 (US9409888, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.0510 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249163 (US9453048, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240879 (US9409888, 28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.289 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228602 (US9340573, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.307 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240895 (US9409888, 17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.307 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240884 (US9409888, 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240892 (US9409888, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.325 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240889 (US9409888, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.375 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240883 (US9409888, 23) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.429 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240900 (US9409888, 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.452 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249162 (US9453048, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249168 (US9453048, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.480 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249161 (US9453048, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228603 (US9340573, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.506 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249169 (US9453048, 11 | US9453048, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249167 (US9453048, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.720 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240902 (US9409888, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 0.801 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240893 (US9409888, 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.815 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228599 (US9340573, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240896 (US9409888, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240897 (US9409888, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.872 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228590 (US9340573, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.888 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240903 (US9409888, 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.899 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM243099 ((S)N((S)-5-(4-Acetylbenzoyl)-1-((6-bro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US10053431 (2018) BindingDB Entry DOI: 10.7270/Q2W097X3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240888 (US9409888, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.02 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228600 (US9340573, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.05 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249166 (US9453048, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249160 (US9453048, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.11 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249172 (US9453048, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.14 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240905 (US9409888, 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.17 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249165 (US9453048, 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.19 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240899 (US9409888, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240898 (US9409888, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.23 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228598 (US9340573, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.24 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249178 (US9453048, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.25 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240881 (US9409888, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.25 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240904 (US9409888, 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.32 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240901 (US9409888, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.38 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240894 (US9409888, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.43 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228596 (US9340573, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.54 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228593 (US9340573, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.57 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240890 (US9409888, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.58 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228601 (US9340573, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.62 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM228594 (US9340573, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.67 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist... | US Patent US9340573 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249169 (US9453048, 11 | US9453048, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Artificial Sequence) | BDBM240882 (US9409888, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.71 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Hoffmann-La Roche Inc. US Patent | Assay Description Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ... | US Patent US9409888 (2016) BindingDB Entry DOI: 10.7270/Q2R78D4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249164 (US9453048, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.84 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM412169 ((3S)-N-[2-[[(3S)-3-[(2,6- difluorophenyl)carbamoyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description For the Bir2 assay, 3.5 nanomolar of 6× Histidine-tagged BIR2 domain (6× Histidine disclosed as SEQ ID NO: 25), corresponding to amino acids 124-240 ... | US Patent US10398702 (2019) BindingDB Entry DOI: 10.7270/Q2VH5R67 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249171 (US9453048, 13 | US9453048, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [124-240] (Homo sapiens (Human)) | BDBM249174 (US9453048, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.11 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi... | US Patent US9453048 (2016) BindingDB Entry DOI: 10.7270/Q2057DV5 | |||||||||||
More data for this Ligand-Target Pair |
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