Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator [G550E] (Homo sapiens (Human)) | BDBM300426 (US10130622, Example 00005) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie S.á.r.l.; Galapagos NV US Patent | Assay Description YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit... | US Patent US10130622 (2018) BindingDB Entry DOI: 10.7270/Q2KD20ZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator [G550E] (Homo sapiens (Human)) | BDBM300427 (US10130622, Example 00006) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 417 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie S.á.r.l.; Galapagos NV US Patent | Assay Description YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit... | US Patent US10130622 (2018) BindingDB Entry DOI: 10.7270/Q2KD20ZB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cystic fibrosis transmembrane conductance regulator [G550E] (Homo sapiens (Human)) | BDBM300428 (BDBM300430 | US10130622, Example 00007) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 496 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie S.á.r.l.; Galapagos NV US Patent | Assay Description YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit... | US Patent US10130622 (2018) BindingDB Entry DOI: 10.7270/Q2KD20ZB | |||||||||||
More data for this Ligand-Target Pair |