Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'POU domain, class 5, transcription factor 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POU domain, class 5, transcription factor 1 (Homo sapiens (Human))	BDBM306793 (US10149840, Compound SR-4277 | US10149840, Series ...) Show SMILES CC1=CC2=NC(CN2C=C1)C(=O)NCCSCc1ccccc1F |c:9,t:1,3| Show InChI InChI=1S/C18H20FN3OS/c1-13-6-8-22-11-16(21-17(22)10-13)18(23)20-7-9-24-12-14-4-2-3-5-15(14)19/h2-6,8,10,16H,7,9,11-12H2,1H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. US Patent					Assay Description An existing amount of the OCT3 protein can be estimated from an amount of a compound free in the extracellular fluid in a method similar to a method ...				US Patent US10149840 (2018) BindingDB Entry DOI: 10.7270/Q24X59V0
					More data for this Ligand-Target Pair
POU domain, class 5, transcription factor 1 (Homo sapiens (Human))	BDBM306794 (US10149840, Compound SR-4229 | US10149840, Series ...) Show SMILES CCOc1ccccc1-n1nnnc1SCc1cn2cc(C)ccc2n1 Show InChI InChI=1S/C18H18N6OS/c1-3-25-16-7-5-4-6-15(16)24-18(20-21-22-24)26-12-14-11-23-10-13(2)8-9-17(23)19-14/h4-11H,3,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. US Patent					Assay Description An existing amount of the OCT3 protein can be estimated from an amount of a compound free in the extracellular fluid in a method similar to a method ...				US Patent US10149840 (2018) BindingDB Entry DOI: 10.7270/Q24X59V0
					More data for this Ligand-Target Pair
POU domain, class 5, transcription factor 1 (Homo sapiens (Human))	BDBM50103514 (CHEBI:4975 | Famotidine | Fluxid | MK-208 | Pepcid...) Show SMILES NC(=N)Nc1nc(CSCCC(=N)NS(N)(=O)=O)cs1 Show InChI InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	US Patent	n/a	n/a	6.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. US Patent					Assay Description An existing amount of the OCT3 protein can be estimated from an amount of a compound free in the extracellular fluid in a method similar to a method ...				US Patent US10149840 (2018) BindingDB Entry DOI: 10.7270/Q24X59V0
					More data for this Ligand-Target Pair