Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50000298 ('2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROX...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Yunnan University Curated by ChEMBL | Assay Description Stabilization of Pdcd4 expressed in human HEK293 cells assessed as inhibition of TPA-induced degradation by luciferase reporter assay | J Nat Prod 74: 1990-5 (2011) Article DOI: 10.1021/np200603g BindingDB Entry DOI: 10.7270/Q2HQ4092 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345541 (CHEMBL1784373 | Cryptocaryol B) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345542 (CHEMBL1784374 | Cryptocaryol C) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345543 (CHEMBL1784375 | Cryptocaryol D) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345544 (CHEMBL1784376 | Cryptocaryol E) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50598483 (CHEMBL5170759) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00189 BindingDB Entry DOI: 10.7270/Q2F76HK5 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345546 (CHEMBL1784378 | Cryptocaryol G) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345547 (CHEMBL1784379 | Cryptocaryol H) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM36609 (Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345540 (CHEMBL1784372 | Cryptocaryol A) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death protein 4 (Homo sapiens (Human)) | BDBM50345545 (CHEMBL1784377 | Cryptocaryol F) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required... | J Nat Prod 74: 1015-20 (2011) Article DOI: 10.1021/np100918z BindingDB Entry DOI: 10.7270/Q2JD4X46 | |||||||||||
More data for this Ligand-Target Pair |