Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase large subunit/subunit M2 B'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit/subunit M2 B (Homo sapiens (Human))	BDBM50497567 (CHEMBL3337770) Show SMILES CCCC(CCC)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@]1(C)O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C19H29N5O5/c1-4-6-11(7-5-2)18(26)28-8-12-19(3,27)14(25)17(29-12)24-10-23-13-15(20)21-9-22-16(13)24/h9-12,14,17,25,27H,4-8H2,1-3H3,(H2,20,21,22)/t12-,14+,17-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant ribonucleotide reductase in presence of varying levels of ATP by Dixon plot				Bioorg Med Chem Lett 24: 5304-9 (2014) Article DOI: 10.1016/j.bmcl.2014.09.046 BindingDB Entry DOI: 10.7270/Q22Z18H9
					More data for this Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit/subunit M2 B (Homo sapiens (Human))	BDBM50214817 (CHEMBL236757 | N6-aminoadenosine) Show SMILES NNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H14N6O4/c11-15-8-5-9(13-2-12-8)16(3-14-5)10-7(19)6(18)4(1-17)20-10/h2-4,6-7,10,17-19H,1,11H2,(H,12,13,15)/t4-,6-,7-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibition of human recombinant ribonucleotide reductase p53R2/M1 expressed in Escherichia coli BL21 (DE3) after 30 mins by [3H]CDP reduction method				Eur J Med Chem 46: 1499-504 (2011) Article DOI: 10.1016/j.ejmech.2011.01.055 BindingDB Entry DOI: 10.7270/Q2K074KT
					More data for this Ligand-Target Pair