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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential protein 5'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential protein 5


(Rattus norvegicus)		BDBM50529421
PNG
(CHEMBL4530872)
Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl
Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)
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PC cid
PC sid
PDB
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Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Goldfinch Bio Inc.

Curated by ChEMBL


Assay Description
Inhibition of rosiglitazone-activated rat TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with holdi...

ACS Med Chem Lett 10: 1579-1585 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00430
BindingDB Entry DOI: 10.7270/Q2DN48HF
More data for this
Ligand-Target Pair