BindingDB PrimarySearch

Found 17 hits Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily A member 6'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50279106 (4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one \| ...) Show SMILES O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Rattus norvegicus)	BDBM50456976 (CHEMBL4207745) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456976 (CHEMBL4207745) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456974 (CHEMBL3621636) Show SMILES Nc1nc(\C=C\CNC(=O)c2cc(Br)c[nH]2)c[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50220547 (4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-ami...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456970 (CHEMBL3261431) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Rattus norvegicus)	BDBM50456975 (CHEMBL4213446) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Rattus norvegicus)	BDBM50456982 (CHEMBL4208517) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Rattus norvegicus)	BDBM50220547 (4,5-Dibromo-1H-pyrrole-2-carboxylic acid [3-(2-ami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Rattus norvegicus)	BDBM50456969 (CHEMBL4202870) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp assay				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456975 (CHEMBL4213446) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456977 (CHEMBL3261430) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456969 (CHEMBL4202870) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456971 (CHEMBL4210636) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456982 (CHEMBL4208517) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50456973 (Clathrodin) Show SMILES Nc1ncc(\C=C\CNC(=O)c2ccc[nH]2)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method				Eur J Med Chem 139: 232-241 (2017) Article DOI: 10.1016/j.ejmech.2017.08.015 BindingDB Entry DOI: 10.7270/Q2668GT4
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 6 (Homo sapiens (Human))	BDBM50067880 (4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one \| 4-me...) Show SMILES COc1c2ccoc2cc2oc(=O)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.87E+5	n/a	n/a	n/a	n/a	n/a
University of Kiel Curated by ChEMBL					Assay Description Blockade of peak K+ currents against Kv1.6 gene				J Med Chem 41: 4542-9 (1998) Article DOI: 10.1021/jm981032o BindingDB Entry DOI: 10.7270/Q2B56HWK
University of Kiel Curated by ChEMBL					More data for this Ligand-Target Pair