BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF15' AND taxid = 9606
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kinesin-like protein KIF15 (Homo sapiens)	BDBM50518447 (CHEMBL4540278) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged Kif15 (N700 residues) (unknown origin) expressed in HeLa cells assessed as reduction in Alexa-594 labelled micr...				Bioorg Med Chem Lett 29: 148-154 (2019) Article DOI: 10.1016/j.bmcl.2018.12.008 BindingDB Entry DOI: 10.7270/Q2Z3230B
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Kinesin-like protein KIF15 (Homo sapiens)	BDBM50085411 (3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged Kif15 (N700 residues) (unknown origin) expressed in HeLa cells assessed as reduction in Alexa-594 labelled micr...				Bioorg Med Chem Lett 29: 148-154 (2019) Article DOI: 10.1016/j.bmcl.2018.12.008 BindingDB Entry DOI: 10.7270/Q2Z3230B
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Kinesin-like protein KIF15 (Homo sapiens)	BDBM50085411 (3-[1-(3,5-Dichloro-4-hydroxy-phenyl)-meth-(Z)-ylid...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged Kif15 ATPase activity (N420 residues) (unknown origin) expressed in HeLa cells using microtubule as substrate p...				Bioorg Med Chem Lett 29: 148-154 (2019) Article DOI: 10.1016/j.bmcl.2018.12.008 BindingDB Entry DOI: 10.7270/Q2Z3230B
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Kinesin-like protein KIF15 (Homo sapiens)	BDBM50518447 (CHEMBL4540278) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal truncated His6-tagged Kif15 (N700 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed a...				Bioorg Med Chem Lett 29: 148-154 (2019) Article DOI: 10.1016/j.bmcl.2018.12.008 BindingDB Entry DOI: 10.7270/Q2Z3230B
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Kinesin-like protein KIF15 (Homo sapiens)	BDBM50085415 (3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged Kif15 ATPase activity (N420 residues) (unknown origin) expressed in HeLa cells using microtubule as substrate p...				Bioorg Med Chem Lett 29: 148-154 (2019) Article DOI: 10.1016/j.bmcl.2018.12.008 BindingDB Entry DOI: 10.7270/Q2Z3230B
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair