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Compile Data Set for Download or QSAR

Found 422 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 6' AND taxid = 9606   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383373
PNG
(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-propyl-8,9-dihy...)
Show SMILES CCC[C@H]1CCOc2cc(cc3nnc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C20H22N8O/c1-3-4-13-7-10-29-18-12-14(11-17-25-26-19(13)28(17)18)15-5-8-21-20(23-15)24-16-6-9-22-27(16)2/h5-6,8-9,11-13H,3-4,7,10H2,1-2H3,(H,21,23,24)/t13-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM560058
PNG
((S)-2-[4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrim...)
Show SMILES CCC(C#N)[C@@H]1CCOc2cc(cc3nnc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383314
PNG
(4-(9-(4-fluorophenoxy)- 8,9-dihydro-7H-6-oxa- 1,2,...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC[C@H](Oc3ccc(F)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H19FN8O2/c1-31-19(7-10-26-31)28-23-25-9-6-17(27-23)14-12-20-29-30-22-18(8-11-33-21(13-14)32(20)22)34-16-4-2-15(24)3-5-16/h2-7,9-10,12-13,18H,8,11H2,1H3,(H,25,27,28)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM560066
PNG
(N-(1-methyl-1H-pyrazol-5-yl)-4-(9-((4-methylthiazo...)
Show SMILES Cc1csc(C[C@H]2CCOc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)n1 |r|
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383383
PNG
(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
Show SMILES Clc1cnn(C[C@H]2CCOc3cc(cc4nnc2n34)-c2ccnc(NC3CCOCC3)n2)c1 |r|
Show InChI InChI=1S/C22H23ClN8O2/c23-16-11-25-30(13-16)12-14-2-8-33-20-10-15(9-19-28-29-21(14)31(19)20)18-1-5-24-22(27-18)26-17-3-6-32-7-4-17/h1,5,9-11,13-14,17H,2-4,6-8,12H2,(H,24,26,27)/t14-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383385
PNG
(4-(9-(3,4-difluorophenoxy)- 8,9-dihydro-7H-6-oxa- ...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC[C@H](Oc3ccc(F)c(F)c3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H18F2N8O2/c1-32-19(5-8-27-32)29-23-26-7-4-17(28-23)13-10-20-30-31-22-18(6-9-34-21(11-13)33(20)22)35-14-2-3-15(24)16(25)12-14/h2-5,7-8,10-12,18H,6,9H2,1H3,(H,26,28,29)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365023
PNG
(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-phenyl-4,5-dihy...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2NC[C@H](Cc3ccccc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H21N9/c1-31-19(8-10-26-31)28-23-24-9-7-18(27-23)16-12-20-25-14-17(11-15-5-3-2-4-6-15)22-30-29-21(13-16)32(20)22/h2-10,12-13,17,25H,11,14H2,1H3,(H,24,27,28)/t17-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365025
PNG
(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-phenyl-4,5-dihy...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2NC[C@@H](c3nnc(c1)n23)c1ccccc1 |r|
Show InChI InChI=1S/C23H20N8/c1-30-20(8-10-26-30)27-19-11-16(7-9-24-19)17-12-21-25-14-18(15-5-3-2-4-6-15)23-29-28-22(13-17)31(21)23/h2-13,18,25H,14H2,1H3,(H,24,27)/t18-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365027
PNG
(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2NC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H20ClN9/c1-32-19(7-9-27-32)29-23-25-8-6-18(28-23)15-11-20-26-13-16(10-14-2-4-17(24)5-3-14)22-31-30-21(12-15)33(20)22/h2-9,11-12,16,26H,10,13H2,1H3,(H,25,28,29)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365030
PNG
(4-(3-benzyl-4,5-dihydro-3H- 1,2,2a1,5- tetraazaace...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2NC[C@H](Cc3ccccc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H22N8/c1-31-21(8-10-27-31)28-20-12-17(7-9-25-20)18-13-22-26-15-19(11-16-5-3-2-4-6-16)24-30-29-23(14-18)32(22)24/h2-10,12-14,19,26H,11,15H2,1H3,(H,25,28)/t19-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365032
PNG
(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2NC[C@H](Cc3ccc(Cl)cc3)c3ncc(c1)n23 |r|
Show InChI InChI=1S/C25H22ClN7/c1-32-23(7-9-30-32)31-22-12-17(6-8-27-22)18-11-21-15-29-25-19(14-28-24(13-18)33(21)25)10-16-2-4-20(26)5-3-16/h2-9,11-13,15,19,28H,10,14H2,1H3,(H,27,31)/t19-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365034
PNG
(4-(3-benzyl-5-methyl-4,5- dihydro-3H-1,2,2a1,5- te...)
Show SMILES CN1C[C@H](Cc2ccccc2)c2nnc3cc(cc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C24H23N9/c1-31-15-18(12-16-6-4-3-5-7-16)23-30-29-21-13-17(14-22(31)33(21)23)19-8-10-25-24(27-19)28-20-9-11-26-32(20)2/h3-11,13-14,18H,12,15H2,1-2H3,(H,25,27,28)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365036
PNG
(4-(3-isobutyl-4,5-dihydro- 3H-1,2,2a1,5- tetraazaa...)
Show SMILES CC(C)C[C@H]1CNc2cc(cc3nnc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C20H23N9/c1-12(2)8-14-11-22-17-9-13(10-18-26-27-19(14)29(17)18)15-4-6-21-20(24-15)25-16-5-7-23-28(16)3/h4-7,9-10,12,14,22H,8,11H2,1-3H3,(H,21,24,25)/t14-/m0/s1
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Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365038
PNG
(4-(3-(4-methoxybenzyl)-4,5- dihydro-3H-1,2,2a1,5- ...)
Show SMILES COc1ccc(C[C@H]2CNc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)cc1 |r|
Show InChI InChI=1S/C24H23N9O/c1-32-20(8-10-27-32)29-24-25-9-7-19(28-24)16-12-21-26-14-17(23-31-30-22(13-16)33(21)23)11-15-3-5-18(34-2)6-4-15/h3-10,12-13,17,26H,11,14H2,1-2H3,(H,25,28,29)/t17-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365040
PNG
(4-(3-(3-fluoro-4- methoxybenzyl)-4,5-dihydro- 3H-1...)
Show SMILES COc1ccc(C[C@H]2CNc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)cc1F |r|
Show InChI InChI=1S/C24H22FN9O/c1-33-20(6-8-28-33)30-24-26-7-5-18(29-24)15-11-21-27-13-16(23-32-31-22(12-15)34(21)23)9-14-3-4-19(35-2)17(25)10-14/h3-8,10-12,16,27H,9,13H2,1-2H3,(H,26,29,30)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383226
PNG
(4-(3-(4-chlorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Show SMILES CN1C[C@H](Cc2ccc(Cl)cc2)c2nnc3cc(cc1n23)-c1ccnc(Nc2ccnn2C)c1 |r|
Show InChI InChI=1S/C25H23ClN8/c1-32-15-19(11-16-3-5-20(26)6-4-16)25-31-30-23-13-18(14-24(32)34(23)25)17-7-9-27-21(12-17)29-22-8-10-28-33(22)2/h3-10,12-14,19H,11,15H2,1-2H3,(H,27,29)/t19-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383227
PNG
(4-(3-(4-chloro-3- fluorobenzyl)-4,5-dihydro- 3H-1,...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2NC[C@H](Cc3ccc(Cl)c(F)c3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H19ClFN9/c1-33-19(5-7-28-33)30-23-26-6-4-18(29-23)14-10-20-27-12-15(22-32-31-21(11-14)34(20)22)8-13-2-3-16(24)17(25)9-13/h2-7,9-11,15,27H,8,12H2,1H3,(H,26,29,30)/t15-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365046
PNG
(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OC[C@@H](Cc3ccccc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H20N8O/c1-30-19(8-10-25-30)27-23-24-9-7-18(26-23)16-12-20-28-29-22-17(11-15-5-3-2-4-6-15)14-32-21(13-16)31(20)22/h2-10,12-13,17H,11,14H2,1H3,(H,24,26,27)/t17-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383231
PNG
(4-(3-benzyl-3,4-dihydro-5- thia-1,2,2a1- triazaace...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2SC[C@H](Cc3ccccc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H20N8S/c1-30-19(8-10-25-30)27-23-24-9-7-18(26-23)16-12-20-28-29-22-17(11-15-5-3-2-4-6-15)14-32-21(13-16)31(20)22/h2-10,12-13,17H,11,14H2,1H3,(H,24,26,27)/t17-/m0/s1
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Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383233
PNG
(4-(3-benzyl-5-ethyl-4,5- dihydro-3H-1,2,2a1,5- tet...)
Show SMILES CCN1C[C@H](Cc2ccccc2)c2nnc3cc(cc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C25H25N9/c1-3-33-16-19(13-17-7-5-4-6-8-17)24-31-30-22-14-18(15-23(33)34(22)24)20-9-11-26-25(28-20)29-21-10-12-27-32(21)2/h4-12,14-15,19H,3,13,16H2,1-2H3,(H,26,28,29)/t19-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383240
PNG
(4-(3-(4-fluorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2NC[C@H](Cc3ccc(F)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H20FN9/c1-32-19(7-9-27-32)29-23-25-8-6-18(28-23)15-11-20-26-13-16(10-14-2-4-17(24)5-3-14)22-31-30-21(12-15)33(20)22/h2-9,11-12,16,26H,10,13H2,1H3,(H,25,28,29)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383242
PNG
(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Show SMILES CN1c2cc(cc3nnc([C@@H](Cc4ccc(Cl)cc4)CC1=O)n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C25H22ClN9O/c1-33-22-13-16(19-7-9-27-25(29-19)30-20-8-10-28-34(20)2)12-21-31-32-24(35(21)22)17(14-23(33)36)11-15-3-5-18(26)6-4-15/h3-10,12-13,17H,11,14H2,1-2H3,(H,27,29,30)/t17-/m0/s1
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Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383245
PNG
(4-(3-((6-methoxypyridin-3- yl)methyl)-4,5-dihydro3...)
Show SMILES COc1ccc(C[C@H]2CNc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)cn1 |r|
Show InChI InChI=1S/C23H22N10O/c1-32-18(6-8-27-32)29-23-24-7-5-17(28-23)15-10-19-25-13-16(22-31-30-20(11-15)33(19)22)9-14-3-4-21(34-2)26-12-14/h3-8,10-12,16,25H,9,13H2,1-2H3,(H,24,28,29)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383251
PNG
(4-(9-((benzyloxy)methyl)- 8,9-dihydro-7H-6-oxa- 1,...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC[C@H](COCc3ccccc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C25H24N8O2/c1-32-21(8-11-27-32)29-25-26-10-7-20(28-25)19-13-22-30-31-24-18(9-12-35-23(14-19)33(22)24)16-34-15-17-5-3-2-4-6-17/h2-8,10-11,13-14,18H,9,12,15-16H2,1H3,(H,26,28,29)/t18-/m1/s1
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Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383254
PNG
(4-(9-(2-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OCC[C@H](Cc3ccccc3Cl)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C25H22ClN7O/c1-32-22(7-10-28-32)29-21-13-16(6-9-27-21)19-14-23-30-31-25-18(8-11-34-24(15-19)33(23)25)12-17-4-2-3-5-20(17)26/h2-7,9-10,13-15,18H,8,11-12H2,1H3,(H,27,29)/t18-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383255
PNG
(4-(3-(4-fluorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Show SMILES CN1C[C@H](Cc2ccc(F)cc2)c2nnc3cc(cc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C24H22FN9/c1-32-14-17(11-15-3-5-18(25)6-4-15)23-31-30-21-12-16(13-22(32)34(21)23)19-7-9-26-24(28-19)29-20-8-10-27-33(20)2/h3-10,12-13,17H,11,14H2,1-2H3,(H,26,28,29)/t17-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM559931
PNG
(4-(3-(4-chloro-3-fluorobenzyl)-5-methyl-4,5-dihydr...)
Show SMILES CN1C[C@H](Cc2ccc(Cl)c(F)c2)c2nnc3cc(cc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383260
PNG
(4-(9-(4-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H21ClN8O/c1-32-20(7-10-27-32)29-24-26-9-6-19(28-24)17-13-21-30-31-23-16(8-11-34-22(14-17)33(21)23)12-15-2-4-18(25)5-3-15/h2-7,9-10,13-14,16H,8,11-12H2,1H3,(H,26,28,29)/t16-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383261
PNG
(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OC[C@H](Cc3ccccc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H21N7O/c1-30-21(8-10-26-30)27-20-12-17(7-9-25-20)18-13-22-28-29-24-19(11-16-5-3-2-4-6-16)15-32-23(14-18)31(22)24/h2-10,12-14,19H,11,15H2,1H3,(H,25,27)/t19-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383264
PNG
(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Show SMILES CN1c2cc(cc3nnc([C@@H](Cc4ccc(Cl)cc4)CC1=O)n23)-c1ccnc(Nc2ccnn2C)c1 |r|
Show InChI InChI=1S/C26H23ClN8O/c1-33-24-14-18(17-7-9-28-21(12-17)30-22-8-10-29-34(22)2)13-23-31-32-26(35(23)24)19(15-25(33)36)11-16-3-5-20(27)6-4-16/h3-10,12-14,19H,11,15H2,1-2H3,(H,28,30)/t19-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383266
PNG
(4-(3-(4-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H19ClN8O/c1-31-19(7-9-26-31)28-23-25-8-6-18(27-23)15-11-20-29-30-22-16(13-33-21(12-15)32(20)22)10-14-2-4-17(24)5-3-14/h2-9,11-12,16H,10,13H2,1H3,(H,25,27,28)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383272
PNG
(4-(3-(4-fluorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OC[C@H](Cc3ccc(F)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H19FN8O/c1-31-19(7-9-26-31)28-23-25-8-6-18(27-23)15-11-20-29-30-22-16(13-33-21(12-15)32(20)22)10-14-2-4-17(24)5-3-14/h2-9,11-12,16H,10,13H2,1H3,(H,25,27,28)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383274
PNG
(4-(3-isobutyl-3,4-dihydro-5- oxa-1,2,2a1- triazaac...)
Show SMILES CC(C)C[C@H]1COc2cc(cc3nnc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C20H22N8O/c1-12(2)8-14-11-29-18-10-13(9-17-25-26-19(14)28(17)18)15-4-6-21-20(23-15)24-16-5-7-22-27(16)3/h4-7,9-10,12,14H,8,11H2,1-3H3,(H,21,23,24)/t14-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383276
PNG
(4-(3-(3-fluoro-4- methoxybenzyl)-3,4-dihydro- 5-ox...)
Show SMILES COc1ccc(C[C@H]2COc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)cc1F |r|
Show InChI InChI=1S/C24H21FN8O2/c1-32-20(6-8-27-32)29-24-26-7-5-18(28-24)15-11-21-30-31-23-16(13-35-22(12-15)33(21)23)9-14-3-4-19(34-2)17(25)10-14/h3-8,10-12,16H,9,13H2,1-2H3,(H,26,28,29)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM559953
PNG
(4-(9-((4-chloro-1H-pyrazol-1-yl)methyl)-8,9-dihydr...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OCC[C@H](Cn3cc(Cl)cn3)c3nnc(c1)n23 |r|
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383280
PNG
(4-(3-(4-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H20ClN7O/c1-31-21(7-9-27-31)28-20-11-16(6-8-26-20)17-12-22-29-30-24-18(14-33-23(13-17)32(22)24)10-15-2-4-19(25)5-3-15/h2-9,11-13,18H,10,14H2,1H3,(H,26,28)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383282
PNG
(4-(3-(3-fluoro-4- methoxybenzyl)-3,4-dihydro- 5-ox...)
Show SMILES COc1ccc(C[C@H]2COc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)c2)cc1F |r|
Show InChI InChI=1S/C25H22FN7O2/c1-32-22(6-8-28-32)29-21-11-16(5-7-27-21)17-12-23-30-31-25-18(14-35-24(13-17)33(23)25)9-15-3-4-20(34-2)19(26)10-15/h3-8,10-13,18H,9,14H2,1-2H3,(H,27,29)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383284
PNG
(4-(3-(4-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Show SMILES COc1ccc(C[C@H]2COc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)cc1 |r|
Show InChI InChI=1S/C24H22N8O2/c1-31-20(8-10-26-31)28-24-25-9-7-19(27-24)16-12-21-29-30-23-17(14-34-22(13-16)32(21)23)11-15-3-5-18(33-2)6-4-15/h3-10,12-13,17H,11,14H2,1-2H3,(H,25,27,28)/t17-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383286
PNG
(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-(2-methylbutyl)...)
Show SMILES CCC(C)C[C@H]1COc2cc(cc3nnc1n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C21H24N8O/c1-4-13(2)9-15-12-30-19-11-14(10-18-26-27-20(15)29(18)19)16-5-7-22-21(24-16)25-17-6-8-23-28(17)3/h5-8,10-11,13,15H,4,9,12H2,1-3H3,(H,22,24,25)/t13?,15-/m0/s1
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Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383288
PNG
(4-(3-(3,4-difluorobenzyl)-3,4- dihydro-5-oxa-1,2,2...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OC[C@H](Cc3ccc(F)c(F)c3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H18F2N8O/c1-32-19(5-7-27-32)29-23-26-6-4-18(28-23)14-10-20-30-31-22-15(12-34-21(11-14)33(20)22)8-13-2-3-16(24)17(25)9-13/h2-7,9-11,15H,8,12H2,1H3,(H,26,28,29)/t15-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383280
PNG
(4-(3-(4-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OC[C@H](Cc3ccc(Cl)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H20ClN7O/c1-31-21(7-9-27-31)28-20-11-16(6-8-26-20)17-12-22-29-30-24-18(14-33-23(13-17)32(22)24)10-15-2-4-19(25)5-3-15/h2-9,11-13,18H,10,14H2,1H3,(H,26,28)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383294
PNG
(4-(9-((4-cyclopropyl-1H- pyrazol-1-yl)methyl)-8,9-...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC[C@H](Cn3cc(cn3)C3CC3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H24N10O/c1-32-20(5-8-26-32)29-24-25-7-4-19(28-24)17-10-21-30-31-23-16(6-9-35-22(11-17)34(21)23)13-33-14-18(12-27-33)15-2-3-15/h4-5,7-8,10-12,14-16H,2-3,6,9,13H2,1H3,(H,25,28,29)/t16-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383296
PNG
(4-(3-(4-fluorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OC[C@H](Cc3ccc(F)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H20FN7O/c1-31-21(7-9-27-31)28-20-11-16(6-8-26-20)17-12-22-29-30-24-18(14-33-23(13-17)32(22)24)10-15-2-4-19(25)5-3-15/h2-9,11-13,18H,10,14H2,1H3,(H,26,28)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383299
PNG
(4-(9-(4-fluorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC[C@H](Cc3ccc(F)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C24H21FN8O/c1-32-20(7-10-27-32)29-24-26-9-6-19(28-24)17-13-21-30-31-23-16(8-11-34-22(14-17)33(21)23)12-15-2-4-18(25)5-3-15/h2-7,9-10,13-14,16H,8,11-12H2,1H3,(H,26,28,29)/t16-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365121
PNG
(4-(9-(3-fluoro-4- methoxybenzyl)-8,9- dihydro-7H-6...)
Show SMILES COc1ccc(C[C@@H]2CCOc3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)cc1F |r|
Show InChI InChI=1S/C25H23FN8O2/c1-33-21(6-9-28-33)30-25-27-8-5-19(29-25)17-13-22-31-32-24-16(7-10-36-23(14-17)34(22)24)11-15-3-4-20(35-2)18(26)12-15/h3-6,8-9,12-14,16H,7,10-11H2,1-2H3,(H,27,29,30)/t16-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383254
PNG
(4-(9-(2-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Show SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OCC[C@H](Cc3ccccc3Cl)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C25H22ClN7O/c1-32-22(7-10-28-32)29-21-13-16(6-9-27-21)19-14-23-30-31-25-18(8-11-34-24(15-19)33(23)25)12-17-4-2-3-5-20(17)26/h2-7,9-10,13-15,18H,8,11-12H2,1H3,(H,27,29)/t18-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365127
PNG
(9-(4-methoxybenzyl)-6- methyl-4-(2-((1-methyl- 1H-...)
Show SMILES COc1ccc(C[C@@H]2CC(=O)N(C)c3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)cc1 |r|
Show InChI InChI=1S/C26H25N9O2/c1-33-23-14-17(20-8-10-27-26(29-20)30-21-9-11-28-34(21)2)13-22-31-32-25(35(22)23)18(15-24(33)36)12-16-4-6-19(37-3)7-5-16/h4-11,13-14,18H,12,15H2,1-3H3,(H,27,29,30)/t18-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM365129
PNG
(9-(4-methoxybenzyl)-6- methyl-4-(2-((1-methyl- 1H-...)
Show SMILES COc1ccc(C[C@@H]2CC(=O)N(C)c3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)c2)cc1 |r|
Show InChI InChI=1S/C27H26N8O2/c1-33-25-15-19(18-8-10-28-22(13-18)30-23-9-11-29-34(23)2)14-24-31-32-27(35(24)25)20(16-26(33)36)12-17-4-6-21(37-3)7-5-17/h4-11,13-15,20H,12,16H2,1-3H3,(H,28,30)/t20-/m1/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383314
PNG
(4-(9-(4-fluorophenoxy)- 8,9-dihydro-7H-6-oxa- 1,2,...)
Show SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC[C@H](Oc3ccc(F)cc3)c3nnc(c1)n23 |r|
Show InChI InChI=1S/C23H19FN8O2/c1-31-19(7-10-26-31)28-23-25-9-6-17(27-23)14-12-20-29-30-22-18(8-11-33-21(13-14)32(20)22)34-16-4-2-15(24)3-5-16/h2-7,9-10,12-13,18H,8,11H2,1H3,(H,25,27,28)/t18-/m0/s1
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TBA

Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 6


(Homo sapiens (Human))		BDBM383316
PNG
(9-benzyl-6-methyl-4-(2-((1- methyl-1H-pyrazol-5- y...)
Show SMILES CN1c2cc(cc3nnc([C@@H](Cc4ccccc4)CC1=O)n23)-c1ccnc(Nc2ccnn2C)n1 |r|
Show InChI InChI=1S/C25H23N9O/c1-32-22-14-17(19-8-10-26-25(28-19)29-20-9-11-27-33(20)2)13-21-30-31-24(34(21)22)18(15-23(32)35)12-16-6-4-3-5-7-16/h3-11,13-14,18H,12,15H2,1-2H3,(H,26,28,29)/t18-/m0/s1
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Assay Description
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2KP85BC
More data for this
Ligand-Target Pair
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