Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' AND taxid = 9913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7/beta-2 (Homo sapiens (Human))	BDBM217353 (Isoflurane) Show SMILES FC(F)OC(Cl)C(F)(F)F Show InChI InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	25
University of Pittsburgh School of Medicine					Assay Description Functional measurements were performed using perforated patch whole cell recordings coupled with a two-barrel drug application system [Liu et al., J....				J Biol Chem 288: 35793-800 (2013) Article DOI: 10.1074/jbc.M113.508333 BindingDB Entry DOI: 10.7270/Q24748QH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Bos taurus)	BDBM50251047 (((R)-1-(3-phenylpropyl)piperidin-3-yl)methyl 2-(3-...) Show SMILES Cc1cc(O)n(c1O)-c1ccccc1C(=O)OC[C@@H]1CCCN(CCCc2ccccc2)C1 |r,wU:18.19,(12.41,-11.72,;10.96,-12.25,;9.68,-11.39,;8.47,-12.34,;6.99,-11.91,;9,-13.78,;10.53,-13.73,;11.48,-14.95,;8.14,-15.06,;9.47,-15.82,;9.47,-17.37,;8.13,-18.14,;6.8,-17.36,;6.81,-15.82,;5.48,-15.05,;5.48,-13.51,;4.14,-15.81,;2.81,-15.04,;1.48,-15.8,;.15,-15.03,;-1.18,-15.8,;-1.18,-17.34,;.15,-18.11,;.15,-19.65,;1.48,-20.42,;2.81,-19.65,;4.15,-20.42,;4.14,-21.96,;5.47,-22.73,;6.81,-21.96,;6.8,-20.41,;5.47,-19.65,;1.48,-17.34,)| Show InChI InChI=1S/C27H32N2O4/c1-20-17-25(30)29(26(20)31)24-14-6-5-13-23(24)27(32)33-19-22-12-8-16-28(18-22)15-7-11-21-9-3-2-4-10-21/h2-6,9-10,13-14,17,22,30-31H,7-8,11-12,15-16,18-19H2,1H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.77E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ohio University Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from bovine alpha7 nAChR expressed in HEK293 cells				Bioorg Med Chem 16: 3816-24 (2008) Article DOI: 10.1016/j.bmc.2008.01.050 BindingDB Entry DOI: 10.7270/Q2DZ0826
					More data for this Ligand-Target Pair