Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribosomal protein S6 kinase alpha-1 [E551G,S637N,G697A] (Rattus norvegicus (rat)) | BDBM25017 (2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Dundee | Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] labe... | Biochem J 401: 29-38 (2007) Article DOI: 10.1042/BJ20061088 BindingDB Entry DOI: 10.7270/Q25Q4TD7 | |||||||||||
More data for this Ligand-Target Pair |