BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 1-alpha/beta/3' AND taxid = 9606
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Signal transducer and activator of transcription 1-alpha/beta/3 (Mus musculus (mouse)-Homo sapiens (Human))	BDBM20282 (4-{[4-(hexylcarbamoyl)-2-(naphthalen-1-yl)-1,3-oxa...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	7.8	22
University of Central Florida College of Medicine					Assay Description STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...				ACS Chem Biol 2: 787-98 (2007) Article DOI: 10.1021/cb7001973 BindingDB Entry DOI: 10.7270/Q29K48HT
University of Central Florida College of Medicine					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 1-alpha/beta/3 (Mus musculus (mouse)-Homo sapiens (Human))	BDBM20283 (2-hydroxy-4-(2-{[(4-methylbenzene)sulfonyl]oxy}ace...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	7.8	22
University of Central Florida College of Medicine					Assay Description STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...				Proc Natl Acad Sci U S A 104: 7391-6 (2007) Article DOI: 10.1073/pnas.0609757104 BindingDB Entry DOI: 10.7270/Q25T3HRN
University of Central Florida College of Medicine					More data for this Ligand-Target Pair