Found 6 hits Enz. Inhib. hit(s) with Target = 'UDP-glucose 4-epimerase' AND taxid = 9606 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
UDP-glucose 4-epimerase
(Homo sapiens (Human)) | BDBM34233
(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee
Curated by ChEMBL
| Assay Description Inhibition of human GalE by HPAEC assay |
Bioorg Med Chem Lett 16: 5744-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.091 BindingDB Entry DOI: 10.7270/Q2RJ4K83 |
More data for this Ligand-Target Pair | |
UDP-glucose 4-epimerase
(Homo sapiens (Human)) | BDBM50194601
(1,2,4-Trichloro-5-(3-iodo-prop-2-ynyloxy)-benzene ...)Show InChI InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee
Curated by ChEMBL
| Assay Description Inhibition of human GalE by HPAEC assay |
Bioorg Med Chem Lett 16: 5744-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.091 BindingDB Entry DOI: 10.7270/Q2RJ4K83 |
More data for this Ligand-Target Pair | |
UDP-glucose 4-epimerase
(Homo sapiens (Human)) | BDBM50117090
((E,E)-Psammaplin A | 3-(3-Bromo-4-hydroxy-phenyl)-...)Show SMILES Oc1ccc(CC(N=O)C(=O)NCCSSCCNC(=O)C(Cc2ccc(O)c(Br)c2)N=O)cc1Br Show InChI InChI=1S/C22H24Br2N4O6S2/c23-15-9-13(1-3-19(15)29)11-17(27-33)21(31)25-5-7-35-36-8-6-26-22(32)18(28-34)12-14-2-4-20(30)16(24)10-14/h1-4,9-10,17-18,29-30H,5-8,11-12H2,(H,25,31)(H,26,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee
Curated by ChEMBL
| Assay Description Inhibition of human GalE by HPAEC assay |
Bioorg Med Chem Lett 16: 5744-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.091 BindingDB Entry DOI: 10.7270/Q2RJ4K83 |
More data for this Ligand-Target Pair | |
UDP-glucose 4-epimerase
(Homo sapiens (Human)) | BDBM50194603
(CHEMBL374772 | diamino(dimethylamino)methyl -((1R,...)Show SMILES CN(C)C(N)(N)OS(=O)(=O)O\C=C1\CC[C@H]2[C@](C)(CC[C@H]3C(C)(C)CCC[C@]23C)[C@H]1CCc1ccoc1 Show InChI InChI=1S/C28H47N3O5S/c1-25(2)14-7-15-27(4)23(25)12-16-26(3)22(10-8-20-13-17-34-18-20)21(9-11-24(26)27)19-35-37(32,33)36-28(29,30)31(5)6/h13,17-19,22-24H,7-12,14-16,29-30H2,1-6H3/b21-19-/t22-,23-,24-,26+,27-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee
Curated by ChEMBL
| Assay Description Inhibition of human GalE by HPAEC assay |
Bioorg Med Chem Lett 16: 5744-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.091 BindingDB Entry DOI: 10.7270/Q2RJ4K83 |
More data for this Ligand-Target Pair | |
UDP-glucose 4-epimerase
(Homo sapiens (Human)) | BDBM50186231
((2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)ac...)Show InChI InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee
Curated by ChEMBL
| Assay Description Inhibition of human GalE by HPAEC assay |
Bioorg Med Chem Lett 16: 5744-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.091 BindingDB Entry DOI: 10.7270/Q2RJ4K83 |
More data for this Ligand-Target Pair | |
UDP-glucose 4-epimerase
(Homo sapiens (Human)) | BDBM20625
(4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | ...)Show InChI InChI=1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dundee
Curated by ChEMBL
| Assay Description Inhibition of human GalE by HPAEC assay |
Bioorg Med Chem Lett 16: 5744-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.091 BindingDB Entry DOI: 10.7270/Q2RJ4K83 |
More data for this Ligand-Target Pair | |