Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50242740![]() (CHEMBL459850 | N-(3-(7-Amino-1-methyl-2-oxo-1,2-di...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Lck by cellular assay | Proc Natl Acad Sci USA 104: 19936-41 (2007) Article DOI: 10.1073/pnas.0707498104 BindingDB Entry DOI: 10.7270/Q24X58QS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340160![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340162![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpiperidin-2-yl)imi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340167![]() ((S,E)-4-(8-amino-3-(1-(4- (dimethylamino)-N-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340079![]() ((S,E)-4-(8-amino-3-(1- cinnamoylpyrrolidin-2- yl)i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340185![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340187![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340188![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340189![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340195![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)im...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340196![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340095![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)im...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340160![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340162![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpiperidin-2-yl)imi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340167![]() ((S,E)-4-(8-amino-3-(1-(4- (dimethylamino)-N-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340079![]() ((S,E)-4-(8-amino-3-(1- cinnamoylpyrrolidin-2- yl)i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340185![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340187![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340188![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340189![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340195![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)im...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340196![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ... | J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q20R9RQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340095![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)im...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340160![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340162![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpiperidin-2-yl)imi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340167![]() ((S,E)-4-(8-amino-3-(1-(4- (dimethylamino)-N-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340079![]() ((S,E)-4-(8-amino-3-(1- cinnamoylpyrrolidin-2- yl)i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340185![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340187![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340188![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340189![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340195![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)im...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340196![]() ((S)-4-(3-(1-acryloylpyrrolidin-2-yl)- 8-aminoimida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US10934296 (2021) BindingDB Entry DOI: 10.7270/Q27947T2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340095![]() ((S)-4-(8-amino-3-(1-but-2- ynoylpyrrolidin-2-yl)im...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 550 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM482158![]() (BDBM50242742 | TAE684) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Lck by cellular assay | Proc Natl Acad Sci USA 104: 19936-41 (2007) Article DOI: 10.1073/pnas.0707498104 BindingDB Entry DOI: 10.7270/Q24X58QS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340118![]() (US10239883, Example 1 | US10934296, Example 1 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340080![]() (US9758524, Example 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340119![]() (US10239883, Example 3 | US10934296, Example 3 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340081![]() (US10239883, Example 4 | US10934296, Example 4 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340082![]() (US10239883, Example 5 | US10934296, Example 5 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50175583![]() (ACP-196 | Acalabrutinib | US10239883, Example 6 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340083![]() (US10239883, Example 7 | US10934296, Example 7 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340121![]() (US10239883, Example 8 | US10934296, Example 8 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340122![]() (US10239883, Example 9 | US10934296, Example 9 | US...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340123![]() (US10239883, Example 10 | US10934296, Example 10 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340084![]() (US10239883, Example 11 | US10934296, Example 11 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340124![]() (US10239883, Example 12 | US10934296, Example 12 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340125![]() (US10934296, Example 13 | US9758524, Example 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340126![]() (US10239883, Example 14 | US10934296, Example 14 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM340127![]() (US10239883, Example 15 | US10934296, Example 15 | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme B.V. US Patent | Assay Description Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M... | US Patent US9758524 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DPQ | |||||||||||
More data for this Ligand-Target Pair |
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