Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247432 (US9453021, 39) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247431 (US9453021, 38) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247439 (US9453021, 113) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247427 (US9453021, 11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247426 (US9453021, 10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247424 (US9453021, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247437 (US9453021, 97) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247436 (US9453021, 71) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247438 (US9453021, 112) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247434 (US9453021, 65) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247429 (US9453021, 15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247428 (US9453021, 14) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247435 (US9453021, 68) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247425 (US9453021, 8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247433 (US9453021, 59) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247430 (US9453021, 17) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2/delta (Rattus norvegicus (Rat)) | BDBM247423 (US9453021, 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | 25 |
Kyowa Hakko Kirin Co., Ltd. US Patent | Assay Description A test compound (20 μL) diluted to 5 times of the final concentration with Binding buffer, [3H]-gabapentin diluted to 100 nmol/L with binding buff... | US Patent US9453021 (2016) BindingDB Entry DOI: 10.7270/Q2251H4B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2 (Rattus norvegicus (Rat)) | BDBM24183 (4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory effect of the compound was measured for [3H]-GABA-uptake from rat synaptosomal membrane | J Med Chem 29: 125-32 (1986) BindingDB Entry DOI: 10.7270/Q21C1VW3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |