Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Free fatty acid receptor 4 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 316 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR | Bioorg Med Chem Lett 24: 3100-3 (2014) Article DOI: 10.1016/j.bmcl.2014.05.012 BindingDB Entry DOI: 10.7270/Q2CC1292 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 540 | n/a | n/a | n/a | n/a |
Piramal Life Sciences Limited Curated by ChEMBL | Assay Description Agonist activity at human GPR40 expressed in CHOK1 cells by fluorescence assay | Bioorg Med Chem Lett 18: 6357-61 (2008) Article DOI: 10.1016/j.bmcl.2008.10.085 BindingDB Entry DOI: 10.7270/Q2FT8KWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 540 | n/a | n/a | n/a | n/a |
Piramal Life Sciences Limited Curated by ChEMBL | Assay Description Agonist activity at GPR40 (unknown origin) | Bioorg Med Chem Lett 18: 6357-61 (2008) Article DOI: 10.1016/j.bmcl.2008.10.085 BindingDB Entry DOI: 10.7270/Q2FT8KWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Piramal Life Sciences Limited Curated by ChEMBL | Assay Description Agonist activity at human GPR40 expressed in CHO cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 18: 6357-61 (2008) Article DOI: 10.1016/j.bmcl.2008.10.085 BindingDB Entry DOI: 10.7270/Q2FT8KWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Agonist activity at human GPR40 expressed in human HEK293 cells assessed as increase in intracellular calcium flux after 10 mins by fluorescence assa... | Bioorg Med Chem 26: 5780-5791 (2018) Article DOI: 10.1016/j.bmc.2018.10.019 BindingDB Entry DOI: 10.7270/Q2319ZKH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
East China Normal University Curated by ChEMBL | Assay Description Agonist activity at human FFA1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based assay | Bioorg Med Chem Lett 29: 848-852 (2019) Article DOI: 10.1016/j.bmcl.2019.01.014 BindingDB Entry DOI: 10.7270/Q21J9F8T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | n/a | n/a | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibition of human recombinant FAAH | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human)) | BDBM22231![]() ((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | n/a | n/a | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist activity at histamine H3 receptor in electrically-stimulated guinea pig ileum | Citation and Details | |||||||||||
More data for this Ligand-Target Pair |