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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for monomerid = 349709   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucagon-like peptide 1 receptor


(Homo sapiens (Human))
BDBM349709
PNG
(2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]pyridin-2-yl...)
Show SMILES OC(=O)c1ccc2nc(CN3CCN(CC3)c3cccc(OCc4ccc(cc4F)C#N)n3)n(C[C@@H]3CCO3)c2c1
Show InChI InChI=1S/C30H29FN6O4/c31-24-14-20(16-32)4-5-22(24)19-41-29-3-1-2-27(34-29)36-11-9-35(10-12-36)18-28-33-25-7-6-21(30(38)39)15-26(25)37(28)17-23-8-13-40-23/h1-7,14-15,23H,8-13,17-19H2,(H,38,39)/t23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.340n/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...


US Patent US10208019 (2019)


BindingDB Entry DOI: 10.7270/Q2WH2S4X
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor


(Homo sapiens (Human))
BDBM349709
PNG
(2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]pyridin-2-yl...)
Show SMILES OC(=O)c1ccc2nc(CN3CCN(CC3)c3cccc(OCc4ccc(cc4F)C#N)n3)n(C[C@@H]3CCO3)c2c1
Show InChI InChI=1S/C30H29FN6O4/c31-24-14-20(16-32)4-5-22(24)19-41-29-3-1-2-27(34-29)36-11-9-35(10-12-36)18-28-33-25-7-6-21(30(38)39)15-26(25)37(28)17-23-8-13-40-23/h1-7,14-15,23H,8-13,17-19H2,(H,38,39)/t23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 7.40n/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...


US Patent US10208019 (2019)


BindingDB Entry DOI: 10.7270/Q2WH2S4X
More data for this
Ligand-Target Pair