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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50009097   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase regulatory protein


(Mus musculus)
BDBM50009097
PNG
(CHEMBL3238298)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)Nc1ccccc1)S(=O)(=O)c1ccc(N)nc1 |r|
Show InChI InChI=1S/C24H25N5O4S2/c1-2-6-21-18-28(35(32,33)23-13-14-24(25)26-17-23)15-16-29(21)20-9-11-22(12-10-20)34(30,31)27-19-7-4-3-5-8-19/h3-5,7-14,17,21,27H,15-16,18H2,1H3,(H2,25,26)/t21-/m0/s1
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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


J Med Chem 57: 3094-116 (2014)


Article DOI: 10.1021/jm5000497
BindingDB Entry DOI: 10.7270/Q2V126BF
More data for this
Ligand-Target Pair