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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50447284   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hexokinase-4


(Mus musculus (Mouse))		BDBM50447284
PNG
(CHEMBL3113993)
Show SMILES OC(c1ccc(cc1)N1CCN(CC1)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H18F6N2O3S/c20-18(21,22)17(28,19(23,24)25)14-6-8-15(9-7-14)26-10-12-27(13-11-26)31(29,30)16-4-2-1-3-5-16/h1-9,28H,10-13H2
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...

J Med Chem 57: 325-38 (2014)


Article DOI: 10.1021/jm4016747
BindingDB Entry DOI: 10.7270/Q2Q241Q5
More data for this
Ligand-Target Pair