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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for monomerid = 50461795   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50461795
PNG
(CHEMBL4228540)
Show SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCCC(O)=O |r,t:19|
Show InChI InChI=1S/C26H38O5/c1-16(27)20-9-10-21-19-8-7-17-15-18(31-24(30)6-4-5-23(28)29)11-13-25(17,2)22(19)12-14-26(20,21)3/h7,18-22H,4-6,8-15H2,1-3H3,(H,28,29)/t18-,19-,20+,21-,22-,25-,26+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.90E+4n/an/an/an/a



Institute of Physiology of the Czech Academy of Sciences

Curated by ChEMBL


Assay Description
Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...

J Med Chem 61: 4505-4516 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00255
BindingDB Entry DOI: 10.7270/Q2Z03BTB
More data for this
Ligand-Target Pair