Compile Data Set for Download or QSAR

Found 8 hits of ec50 for UniProtKB: P12746   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50527018 (CHEMBL4517457) Show SMILES O=C(CC1CCCC1)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C13H19NO4/c15-10(7-9-3-1-2-4-9)8-12(16)14-11-5-6-18-13(11)17/h9,11H,1-8H2,(H,14,16)/t11-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Agonist activity at Aliivibrio fischeri LuxR by luminescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50241431 ((S)-2-(3-nitrophenyl)-N-(2-oxo-tetrahydrofuran-3-y...) Show SMILES [O-][N+](=O)c1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C12H12N2O5/c15-11(13-10-4-5-19-12(10)16)7-8-2-1-3-9(6-8)14(17)18/h1-3,6,10H,4-5,7H2,(H,13,15)/t10-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Vibrio fischeri luxR receptor in absence of natural autoinducer				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50526983 (CHEMBL4535946) Show SMILES CC(C)CC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C11H17NO4/c1-7(2)5-8(13)6-10(14)12-9-3-4-16-11(9)15/h7,9H,3-6H2,1-2H3,(H,12,14)/t9-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Agonist activity at Aliivibrio fischeri LuxR by luminescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50526984 (CHEMBL4579576) Show SMILES O=C(CC1CCCCC1)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C14H21NO4/c16-11(8-10-4-2-1-3-5-10)9-13(17)15-12-6-7-19-14(12)18/h10,12H,1-9H2,(H,15,17)/t12-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Agonist activity at Aliivibrio fischeri LuxR by luminescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50527005 (CHEMBL15908) Show SMILES O=C(CCCC1CCCCC1)NC1CCOC1=O Show InChI InChI=1S/C14H23NO3/c16-13(15-12-9-10-18-14(12)17)8-4-7-11-5-2-1-3-6-11/h11-12H,1-10H2,(H,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Agonist activity at Aliivibrio fischeri LuxR by luminescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389278 (CHEMBL2063592) Show SMILES CCCCCc1nnnn1C1CCOC1=O Show InChI InChI=1S/C10H16N4O2/c1-2-3-4-5-9-11-12-13-14(9)8-6-7-16-10(8)15/h8H,2-7H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Agonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as activation of 3-oxoC6-HSL-induced quor...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50350712 (CHEMBL1812084) Show SMILES [O-][N+](=O)c1cccc(CC(=O)N[C@H]2CCSC2=O)c1 |r| Show InChI InChI=1S/C12H12N2O4S/c15-11(13-10-4-5-19-12(10)16)7-8-2-1-3-9(6-8)14(17)18/h1-3,6,10H,4-5,7H2,(H,13,15)/t10-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHL				Bioorg Med Chem 19: 4820-8 (2011) Article DOI: 10.1016/j.bmc.2011.06.071 BindingDB Entry DOI: 10.7270/Q27D2W47
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri)	BDBM50389279 (CHEMBL2063593) Show SMILES CCCCCCc1nnnn1C1CCOC1=O Show InChI InChI=1S/C11H18N4O2/c1-2-3-4-5-6-10-12-13-14-15(10)9-7-8-17-11(9)16/h9H,2-8H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a
INSA Lyon Curated by ChEMBL					Assay Description Agonist activity at Vibrio fischeri LuxR expressed in Escherichia coli NM522 coexpressing LuxCDABE assessed as activation of 3-oxoC6-HSL-induced quor...				Bioorg Med Chem 20: 4727-36 (2012) Article DOI: 10.1016/j.bmc.2012.06.007 BindingDB Entry DOI: 10.7270/Q2DR2WK2
					More data for this Ligand-Target Pair