Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thyrotropin receptor (Homo sapiens (Human)) | BDBM50189778 (CHEMBL211405 | N-tert-butyl-5-amino-4-(3-methoxyph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Agonist activity at TSHR expressed in HEK293 EM cells measured by intracellular cAMP accumulation | J Med Chem 49: 3888-96 (2006) Article DOI: 10.1021/jm060247s BindingDB Entry DOI: 10.7270/Q29886MR | |||||||||||
More data for this Ligand-Target Pair |